Results 111 to 120 of about 7,745 (211)

Sex dimorphism of cortical water diffusion in normal aging measured by magnetic resonance imaging

Frontiers in Aging Neuroscience, 2013
BackgroundThe purpose of this study was to examine sex dimorphism in water diffusion in the brain throughout the normal aging process by magnetic resonance imaging. MethodsDiffusion-weighted images covering the majority of the brain were acquired from 77
Shu-Hang eNg, Wen-Chiun eHsu, Yau-Yau eWai, Jiann-Der eLee, Hsiao-Lung eChan, YaoLiang eChen, Hon-Chung eFung, YihRu eWu, Ming-Lun eTsai, Jiun-Jie eWang, Jiun-Jie eWang, Jiun-Jie eWang   +11 more
doaj   +1 more source

Simulation‐Informed Evaluation of Microvascular Parameter Mapping for Diffusion MR Imaging of Solid Tumours

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 387-402, July 2026.
ABSTRACT Purpose We aim to inform the design of new diffusion MRI (dMRI) approaches for microvasculature quantification that enhance the biological specificity of imaging towards cancer. Methods We adopted simulation‐informed modelling of the vascular dMRI signal. We synthesised signals from 1500 synthetic vascular networks, for a variety of protocols (
Anna Kira Voronova, Olivia Prior, Athanasios Grigoriou, Francesc Salvà, Elena Elez, Luz M. Atlagich, Roser Sala‐Llonch, Marco Palombo, Els Fieremans, Dmitry S. Novikov, Raquel Perez‐Lopez, Francesco Grussu   +11 more
wiley   +1 more source

Diffusion Kurtosis Imaging of Substantia Nigra Is a Sensitive Method for Early Diagnosis and Disease Evaluation in Parkinson’s Disease

Parkinson's Disease, 2015
Background. To diagnose Parkinson disease (PD) in an early stage and accurately evaluate severity, it is important to develop a sensitive method for detecting structural changes in the substantia nigra (SN). Method.
Guohua Zhang, Yuhu Zhang, Chengguo Zhang, Yukai Wang, Guixian Ma, Kun Nie, Haiqun Xie, Jianping Liu, Lijuan Wang   +8 more
doaj   +1 more source

Assessing Measurement Repeatability of a Novel Anisotropic Phantom for Advanced Diffusion MRI Models

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 339-348, July 2026.
ABSTRACT Purpose Diffusion MRI is widely used to characterize tissue microstructure, but standardization remains challenging, particularly for advanced models or regions with crossing fibers. Phantoms provide controlled environments to assess measurement repeatability independent of biological variability.
Lauren Stephens, Sofia Chavez, Fergal Kerins, Michael D. Noseworthy   +3 more
wiley   +1 more source

Reconstructing diffusion kurtosis tensors from sparse noisy measurements [PDF]

, 2010
Diffusion kurtosis imaging (DKI) is a recent MRI based method that can quantify deviation from Gaussian behavior using a kurtosis tensor. DKI has potential value for the assessment of neurologic diseases.
Liu, Y, Yizhou Yu, Wei, S, Yugang Liu, Yu, Y, Siming Wei, Jiang, Q, Quan Jiang   +7 more
core   +1 more source

Characterizing the Diffusion Properties of Prostate Tissue Using Paired MR Microscopy and Multidimensional Diffusion MRI

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 349-365, July 2026.
ABSTRACT Purpose To characterize the diffusion properties of prostate epithelium and stroma in benign tissue and cancer. Methods Paired MR microscopy (20 μm) and multidimensional diffusion MRI (dMRI) (160 μm, b = 1000–2000 s/mm2, ∆ = 15–120 ms) were performed at 16.4 T on 17 fixed prostate tissue samples (14× benign, 2× Gleason 3 + 3, 1× Gleason 4 + 4).
Adam Phipps, Nyoman D. Kurniawan, Geoff Watson, Paul Sved, Samson Dowland, Eleftheria Panagiotaki, David Atkinson, Roger Bourne   +7 more
wiley   +1 more source

Simulation Study of Kurtosis Measurements in MR Diffusion Kurtosis Imaging

, 2008
Monte Carlo simulation was performed in 1D space to study the spin diffusion, kurtosis characteristics, spin dephasing and MR signal attenuation in compartment-restricted diffusion environment. The apparent kurtosis was computed based on DKI formulation
Cheng, KH, Wu, EX
core  

Optimization of Diffusion MRI With Consideration of the Signal Decay in Biological Tissues

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 460-468, July 2026.
ABSTRACT Purpose Devising methodology to characterize and optimize acquisition schemes for biological tissues, such as the prostate, that produce model‐based synthetic diffusion‐weighted images and derived model parameters with predictable SNR improvement. Methods The averaging effect (AE) in synthetic diffusion‐weighted images obtained through fitting
Stefan Kuczera, Stephan E. Maier
wiley   +1 more source

The Role of Dendritic Spines in Water Exchange Measurements With Diffusion MRI: Double Diffusion Encoding and Free‐Waveform MRI

NMR in Biomedicine, Volume 39, Issue 7, July 2026.
Geometric water exchange in dendritic spines imparts a similar signature on diffusion‐MRI signals as permeative, transmembrane water exchange. Current diffusion MRI methods are non‐specific to geometric and permeative exchange. This work proposes a method to disentangle these two modes of exchange, yielding both more accurate estimates of permeative ...
Arthur Chakwizira, Kadir Şimşek, Filip Szczepankiewicz, Marco Palombo, Markus Nilsson   +4 more
wiley   +1 more source

Magnetic Resonance Imaging at 14 Tesla of Prostate Biopsies Obtained after Prostatectomy

NMR in Biomedicine, Volume 39, Issue 7, July 2026.
Fresh prostate biopsies were imaged using a 14 T vertical bore MRI scanner, and the effects of long gradient separation Δ (10–400 ms) were explored. At Δ longer than 10 ms, the percentage of voxels where the Akaike information criteria (AICc) favored a monoexponential model increased, and the apparent diffusion coefficient (ADC) lowered compared to Δ ...
Fredrik Langkilde, Stefan Kuczera, Vasiliki Spyratou, Johan Stranne, Stephan E. Maier   +4 more
wiley   +1 more source