The Association of Apparent Myelin Water Fraction With Diffusional Kurtosis and Biophysical Modeling Parameters. [PDF]
NMR BiomedWe investigated associations between a panel of diffusion MRI metrics and myelin content, using ViSTa apparent myelin water fraction (aMWF) as a proxy for myelin. Fractional anisotropy (FA) showed a robust association with aMWF; however, more advanced metrics including radial kurtosis (K⊥) and axonal water fraction (f) had stronger correlations ...
Moss HG +5 more
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Diffusion MRI reveals amyloid plaque–associated cellular signatures through spatial transcriptomic integration [PDF]
Alzheimers DementAbstract INTRODUCTION Amyloid plaque deposition is a defining feature of Alzheimer's disease (AD), yet how plaque‐associated cellular alterations are reflected in noninvasive imaging remains unclear. METHODS We integrated high‐resolution diffusion magnetic resonance imaging (dMRI) with spatial transcriptomics (ST) in an AD mouse model.
Han X +10 more
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High-Resolution Diffusion Kurtosis Imaging of Hippocampus Subfields Across the Healthy Lifespan. [PDF]
NMR BiomedDevelopmental and aging changes were examined in the hippocampus using 1 mm isotropic diffusion kurtosis imaging in 363 participants aged 5–90 years. HippUnfold enabled automated subfield segmentation and unfolded hippocampal maps. Whole‐hippocampus showed distinct lifespan trajectories: volume, quadratic; MD, negative Gamma Variate; FA, positive Gamma
Stack-Sanchez P +3 more
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NeuroImage: Clinical, 2016 Magnetic resonance based diffusion imaging has been gaining more utility and clinical relevance over the past decade. Using conventional echo planar techniques, it is possible to acquire and characterize water diffusion within the central nervous system (
Chris J. Conklin +11 more
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FMultifunctional magnetic resonance imaging for the assessment of renal pathological alterations in IgA nephropathy [PDF]
BMC NephrologyBackground We aimed to evaluate the application value of multiparametric diffusion weighted magnetic resonance imaging (MRI) for the assessment and risk stratification of renal histopathological injuries in patients with IgA nephropathy (IgAN), as an ...
Aiqun Chen +5 more
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Diagnostic value of diffusion kurtosis imaging for brain injury in term neonates with hypoxic–ischemic encephalopathy [PDF]
Frontiers in NeuroscienceBackgroundNeonatal hypoxic–ischemic encephalopathy (HIE) stands as a primary cause of neonatal brain injury, mortality, and long-term neurodevelopmental impairment, imposing a considerable burden on public health systems worldwide.
Xueyuan Wang +13 more
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Performance Comparison of Diffusion Kurtosis Imaging (DKI), Neurite Orientation Dispersion and Density Imaging (NODDI), and Diffusion Microstructure Imaging (DMI) in Predicting Adult-Type Glioma Subtype—A Pilot Study [PDF]
CancersUwe Klose +2 more
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Frontiers in Aging Neuroscience, 2021 Neurological deficits after stroke are closely related to white matter microstructure damage. However, secondary changes in white matter microstructure after pontine infarction (PI) in the whole brain remain unclear.
Ying Wei +11 more
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Survival Prediction Analysis in Glioblastoma With Diffusion Kurtosis Imaging
Frontiers in Oncology, 2021 Simple SummaryGlioblastoma (GBM) is the most common and aggressive primary brain tumor. Diffusion kurtosis imaging (DKI) has characterized non-Gaussian diffusion behaviors in brain normal tissue and gliomas, but there are very limited efforts in ...
Yuan Li +8 more
doaj +1 more source
Characterization of Breast Tumors Using Diffusion Kurtosis Imaging (DKI) [PDF]
PLoS ONE, 2014 Jiani Hu, Guanwu Li, Dongmei Wu
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