Results 11 to 20 of about 2,367 (150)

Assessing Measurement Repeatability of a Novel Anisotropic Phantom for Advanced Diffusion MRI Models. [PDF]

Magn Reson Med
ABSTRACT Purpose Diffusion MRI is widely used to characterize tissue microstructure, but standardization remains challenging, particularly for advanced models or regions with crossing fibers. Phantoms provide controlled environments to assess measurement repeatability independent of biological variability.
Stephens L, Chavez S, Kerins F, Noseworthy MD.   +3 more
europepmc   +2 more sources

Brain Alterations Linked to the MPTP Mouse Model of Parkinson's Disease Uncovered by Diffusion Kurtosis Imaging and Magnetic Resonance Spectroscopy. [PDF]

CNS Neurosci Ther
In MPTP‐treated mice, DKI and 1H‐MRS revealed increased hippocampal and thalamic diffusivity with reduced striatal Glu/tCr and Glx/tCr at 24 h. By 72 h, cortical, striatal, and thalamic diffusivity rose, with partial hippocampal recovery. Elevated Tau/tCr and hippocampal metabolite alterations paralleled neuronal loss and gliosis, supporting DKI/1H‐MRS
Modi A, Maria S, Ruda-Kucerova J, Drazanova E, Harastova-Pavlova I, Sejnoha Minsterova A, Kovacovicova K, Havas D, Rektorova I, Outeiro TF, Khairnar A.   +10 more
europepmc   +2 more sources

Performances of diffusion kurtosis imaging and diffusion tensor imaging in detecting white matter abnormality in schizophrenia

NeuroImage: Clinical, 2015
Diffusion kurtosis imaging (DKI) is an extension of diffusion tensor imaging (DTI), exhibiting improved sensitivity and specificity in detecting developmental and pathological changes in neural tissues.
Jiajia Zhu, Chuanjun Zhuo, Wen Qin, Di Wang, Xiaomei Ma, Yujing Zhou, Chunshui Yu   +6 more
doaj   +3 more sources

Non-invasive identification of KRAS mutation in rectal cancer using hybrid intravoxel incoherent motion and diffusion kurtosis model [PDF]

World Journal of Surgical Oncology
Background and purpose Sarcoma Viral Oncogene Homologue (KRAS) mutation status is a crucial biomarker in rectal cancer as KRAS mutations confer resistance to anti-EGFR targeted therapies and influence chemotherapy selection, affecting treatment decisions
Jie Yuan, Mingrong Yao, Ziyuan Wang, Wenli Tan, Yun Zhang, Huamei Yan, Mengxiao Liu, Kun Liu, Hangjun Gong, Songhua Zhan   +9 more
doaj   +2 more sources

Multiparametric MRI in primary cerebral lymphoma: Correlation between diffusion kurtosis imaging (DKI), dynamic contrast enhanced (DCE) and dynamic Susceptibility contrast (DSC) MRI techniques

Physica Medica
The aim of our study is to verify the reliability of Diffusion Kurtosis Imaging (DKI) parameters through correlation with perfusion metrics obtained by Dynamic Contrast Enhanced (DCE)- and Dynamic Susceptibility Contrast (DSC)-MRI techniques in histologic-proven primary central nervous system lymphoma (PCNSL).A total of 15 lesions were analyzed in ...
Valerio Da Ros, Valentina Ferrazzoli, Eliseo Picchi   +2 more
exaly   +5 more sources

Widespread White Matter Microstructure Alterations Based on Diffusion Tensor Imaging and Diffusion Kurtosis Imaging in Patients With Pontine Infarction

Frontiers in Aging Neuroscience, 2021
Neurological deficits after stroke are closely related to white matter microstructure damage. However, secondary changes in white matter microstructure after pontine infarction (PI) in the whole brain remain unclear.
Ying Wei, Caihong Wang, Jingchun Liu, Peifang Miao, Sen Wei, Yingying Wang, Luobing Wu, Boyan Xu, Shaoqiang Han, Yarui Wei, Kaiyu Wang, Jingliang Cheng   +11 more
doaj   +1 more source

Survival Prediction Analysis in Glioblastoma With Diffusion Kurtosis Imaging

Frontiers in Oncology, 2021
Simple SummaryGlioblastoma (GBM) is the most common and aggressive primary brain tumor. Diffusion kurtosis imaging (DKI) has characterized non-Gaussian diffusion behaviors in brain normal tissue and gliomas, but there are very limited efforts in ...
Yuan Li, Yuan Li, Michelle M. Kim, Daniel R. Wahl, Theodore S. Lawrence, Hemant Parmar, Yue Cao, Yue Cao, Yue Cao   +8 more
doaj   +1 more source

Diagnostic performance between MR amide proton transfer (APT) and diffusion kurtosis imaging (DKI) in glioma grading and IDH mutation status prediction at 3 T [PDF]

European Journal of Radiology, 2021
Accurate glioma grading and IDH mutation status prediction are critically essential for individualized preoperative treatment decisions. This study aims to compare the diagnostic performance of magnetic resonance (MR) amide proton transfer (APT) and diffusion kurtosis imaging (DKI) in glioma grading and IDH mutation status prediction.Fifty-one glioma ...
Zongwei, Xu, Chao, Ke, Jie, Liu, Shijie, Xu, Lujun, Han, Yadi, Yang, Long, Qian, Xin, Liu, Hairong, Zheng, Xiaofei, Lv, Yin, Wu   +10 more
openaire   +2 more sources

Diffusion Kurtosis Imaging of Microstructural Changes in Gray Matter Nucleus in Parkinson Disease

Frontiers in Neurology, 2020
Objective: To explore the microstructural damage of extrapyramidal system gray matter nuclei in Parkinson disease (PD) using diffusion kurtosis imaging (DKI).Materials and Methods: We enrolled 35 clinically confirmed PD patients and 23 healthy volunteers.
Gao Bingbing, Zhou Yujing, Miao Yanwei, Dong Chunbo, Wang Weiwei, Tian Shiyun, Liu Yangyingqiu, Shang Jin, Song Qingwei, Liu Ailian, Xie Lizhi   +10 more
doaj   +1 more source

Recent Developments in Fast Kurtosis Imaging

Frontiers in Physics, 2017
Diffusion kurtosis imaging (DKI) is an extension of the popular diffusion tensor imaging (DTI) technique. DKI takes into account leading deviations from Gaussian diffusion stemming from a number of effects related to the microarchitecture and ...
Brian Hansen, Sune N. Jespersen, Sune N. Jespersen   +2 more
doaj   +1 more source