Results 101 to 110 of about 24,691,873 (342)

A Solvable Nonlinear Reaction-Diffusion Model

open access: yes, 1993
We construct a coupled set of nonlinear reaction-diffusion equations which are exactly solvable. The model generalizes both the Burger equation and a Boltzman reaction equation recently introduced by Th. W. Ruijgrok and T. T.
Blanchard   +7 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effects of pressure on diffusion and vacancy formation in MgO from non-empirical free-energy integrations

open access: yes, 1997
The free energies of vacancy pair formation and migration in MgO were computed via molecular dynamics using free-energy integrations and a non-empirical ionic model with no adjustable parameters.
A. De Vita   +33 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Social network information diffusion model based on user’s influence and interesting

open access: yesTongxin xuebao, 2017
A new non-topological information diffusion model of social network was proposed,called non-topological influence-interest diffusion model (NT-II).Representation learning was exploited to construct two hidden spaces for NT-II,called the user-influence ...
Rui WANG   +4 more
doaj  

High‐performance diffusion model for inverse design of high Tc superconductors with effective doping and accurate stoichiometry

open access: yesInfoMat
The pursuit of designing superconductors with high Tc has been a long‐standing endeavor. However, the widespread incorporation of doping in high Tc superconductors significantly impacts electronic structure, intricately influencing Tc.
Chengquan Zhong   +8 more
doaj   +1 more source

A non-equilibrium thermodynamics model for combined adsorption and diffusion processes in micro- and nanopores

open access: yes, 2012
A non-equilibrium thermodynamics model able to analyze the combined effect of diffusion and adsorption in porous materials is proposed. The model considers the coupled dynamics of the diffusive phase, described by a diffusion type equation, and the ...
Grzywna, Z. J.   +2 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Fourier Ptychographic Microscopy Reconstruction Method Based on Residual Local Mixture Network

open access: yesSensors
Fourier Ptychographic Microscopy (FPM) is a microscopy imaging technique based on optical principles. It employs Fourier optics to separate and combine different optical information from a sample.
Yan Wang   +3 more
doaj   +1 more source

Theoretical description of the ligand function for ionoselective electrodes reversible to metal anion complexes. 1. Lower detection limit and its determining factors

open access: yesЖурнал Белорусского государственного университета: Химия, 2020
Within the framework of the steady-state diffusion model, the theoretical description for the thiocyanate ion lower detection limit (LDL) by the tetrathiocyanatozincate selective electrode, has been presented.
Vladimir V. Egorov   +3 more
doaj   +1 more source

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