Results 91 to 100 of about 15,549,974 (248)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Trans-Diff: Heterogeneous Domain Adaptation for Remote Sensing Segmentation With Transfer Diffusion
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingDomain adaptation has been demonstrated to be an important technique to reduce the expensive annotation costs for remote sensing segmentation. However, for remote sensing images (RSIs) acquired from different imaging modalities with significant ...
Yuhan Kang +4 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Robust estimator framework in diffusion tensor imaging [PDF]
, 2013 Diffusion of water molecules in the human brain tissue has strong similarities with diffusion in porous media. It is affected by different factors such as restrictions and compartmentalization, interaction with membrane walls, strong anisotropy imposed ...
Grinberg, Farida +2 more
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Energies, 2016 A new battery simulator based on a hybrid model is proposed in this paper for dynamic discharging behavior and runtime predictions in existing electronic simulation environments, e.g., PSIM, so it can help power circuit designers to develop and optimize ...
Lan-Rong Dung +4 more
doaj +1 more source
Ambigram Generation by a Diffusion Model
, 2023 Ambigrams are graphical letter designs that can be read not only from the original direction but also from a rotated direction (especially with 180 degrees). Designing ambigrams is difficult even for human experts because keeping their dual readability from both directions is often difficult. This paper proposes an ambigram generation model.
Takahiro Shirakawa, Seiichi Uchida
openaire +2 more sources
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length
Advanced SciencePeptides are recognized as next‐generation therapeutic drugs due to their unique properties and are essential for treating human diseases. In recent years, a number of deep generation models for generating peptides have been proposed and have shown great
Zhenjie Luo +5 more
doaj +1 more source
Assessing Cognitive Processes with Diffusion Model Analyses: A Tutorial based on fast-dm-30
Frontiers in Psychology, 2015 Diffusion models can be used to infer cognitive processes involved in fast binary decision tasks. The model assumes that information is accumulated continuously until one of two thresholds is hit.
Andreas eVoss +2 more
doaj +1 more source