Results 101 to 110 of about 15,549,974 (248)

Mirror Diffusion Models

open access: yesCoRR, 2023
Diffusion models have successfully been applied to generative tasks in various continuous domains. However, applying diffusion to discrete categorical data remains a non-trivial task. Moreover, generation in continuous domains often requires clipping in practice, which motivates the need for a theoretical framework for adapting diffusion to constrained
openaire   +3 more sources

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Oxygen diffusion through perovskite membranes [PDF]

open access: yes, 2005
The oxygen permeation flux through the perovskite membrane made of Ba0.5Sr0.5Co0.8Fe0.2O3-δ (BSCF) has been measured as a function of both the temperature and the oxygen pressure gradient across the membrane.
Caro, Jürgen   +3 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Rolling Diffusion Models

open access: yesCoRR
Diffusion models have recently been increasingly applied to temporal data such as video, fluid mechanics simulations, or climate data. These methods generally treat subsequent frames equally regarding the amount of noise in the diffusion process. This paper explores Rolling Diffusion: a new approach that uses a sliding window denoising process.
David Ruhe   +3 more
openaire   +4 more sources

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Knowledge-Driven and Diffusion Model-Based Methods for Generating Historical Building Facades: A Case Study of Traditional Minnan Residences in China

open access: yesInformation
The preservation of historical traditional architectural ensembles faces multifaceted challenges, and the need for facade renovation and updates has become increasingly prominent. In conventional architectural updating and renovation processes, assessing
Sirui Xu, Jiaxin Zhang, Yunqin Li
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mitigate Target-Level Insensitivity of Infrared Small Target Detection via Posterior Distribution Modeling

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Infrared small target detection (IRSTD) aims to segment small targets from infrared clutter background. Existing methods mainly focus on discriminative approaches, i.e., a pixel-level front-background binary segmentation. Since infrared small targets are
Haoqing Li   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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