Results 131 to 140 of about 757,960 (318)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

PFG-NMR studies of ATP diffusion in PEG-DA hydrogels and aqueous solutions of PEG-DA polymers

open access: yes, 2017
Adenosine triphosphate (ATP) is the major carrier of chemical energy in cells. The diffusion of ATP in hydrogels, which have a structural resemblance to the natural extracellular matrix, is therefore of great importance to understand many biological ...
Southan, Alexander, Majer, Günter
core  

A robust and effective framework for 3D scene reconstruction and high-quality rendering in nasal endoscopy surgery

open access: yesFrontiers in Neurorobotics
In nasal endoscopic surgery, the narrow nasal cavity restricts the surgical field of view and the manipulation of surgical instruments. Therefore, precise real-time intraoperative navigation, which can provide precise 3D information, plays a crucial role
Xueqin Ji   +7 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

A percolation model of eco-innovation diffusion: the relationship between diffusion, learning economies and subsidies [PDF]

open access: yes
An obstacle to the widespread adoption of environmentally friendly energy technologies such as stationary and mobile fuel cells is their high upfront costs. While much lower prices seem to be attainable in the future due to learning curve cost reductions
Simona Cantono, Gerald Silverberg
core  

Modelling of Innovation Diffusion

open access: yesOperations Research and Decisions, 2010
Since the publication of the Bass model in 1969, research on the modelling of the diffusion of innovation resulted in a vast body of scientific literature consisting of articles, books, and studies of real-world applications of this model. The main objective of the diffusion model is to describe a pattern of spread of innovation among potential ...
Kijek, Arkadiusz, Kijek, Tomasz
openaire   +2 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

The effect of framework flexibility on diffusion of small molecules in the metal-organic framework IRMOF-1

open access: yes, 2009
Many efforts have been made to model adsorption and diffusion processes in metalorganic frameworks (MOFs) in the past several years. In most of these studies, the framework has been kept rigid.
Dubbeldam, David   +2 more
core  

Diffusion processes and event history analysis [PDF]

open access: yes
Several authors (e.g., Brüderl, Diekmann, Yamaguchi) derive hazard rate models of event history analysis from social diffusion processes. This paper also focuses on the integration of diffusion research and survival analysis.
Norman Braun, Henriette Engelhardt
core   +2 more sources

Social network information diffusion model based on user’s influence and interesting

open access: yesTongxin xuebao, 2017
A new non-topological information diffusion model of social network was proposed,called non-topological influence-interest diffusion model (NT-II).Representation learning was exploited to construct two hidden spaces for NT-II,called the user-influence ...
Rui WANG   +4 more
doaj  

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