Results 51 to 60 of about 292,211 (290)

Simultaneous in vivo positron emission tomography and magnetic resonance imaging [PDF]

open access: yes, 2008
Positron emission tomography (PET) and magnetic resonance imaging (MRI) are widely used in vivo imaging technologies with both clinical and biomedical research applications.
Catana, Ciprian   +7 more
core   +2 more sources

MR scanner systems should be adequately characterized in diffusion-MRI of the breast. [PDF]

open access: yesPLoS ONE, 2014
Breast imaging represents a relatively recent and promising field of application of quantitative diffusion-MRI techniques. In view of the importance of guaranteeing and assessing its reliability in clinical as well as research settings, the aim of this ...
Marco Giannelli   +8 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Comparison of MR cytometry methods in predicting immunohistochemical factor status and molecular subtypes of breast cancer

open access: yesRadiology and Oncology
First evaluation of the performance of MR cytometry incorporating transcytolemmal water exchange in predicting immunohistochemical factor status and molecular subtypes of breast cancer.
Wu Lei   +10 more
doaj   +1 more source

Diffusion MRI in the heart [PDF]

open access: yesNMR in Biomedicine, 2015
Diffusion MRI provides unique information on the structure, organization, and integrity of the myocardium without the need for exogenous contrast agents. Diffusion MRI in the heart, however, has proven technically challenging because of the intrinsic non‐rigid deformation during the cardiac cycle, displacement of the myocardium due to respiratory ...
Mekkaoui, Choukri   +4 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

On the dynamics of structural connectivity of the motor network during interactive rehabilitation in the early recovery period after stroke

open access: yesСибирский научный медицинский журнал
Stroke leads not only to local damage but also to large-scale reorganization of brain networks, including motor regions and interhemispheric interactions.
D. A. Novikov   +4 more
doaj   +1 more source

The road to breast cancer screening with diffusion MRI

open access: yesFrontiers in Oncology, 2023
Breast cancer is the leading cause of cancer in women with a huge medical, social and economic impact. Mammography (MMG) has been the gold standard method until now because it is relatively inexpensive and widely available.
Mami Iima, Mami Iima, Denis Le Bihan
doaj   +1 more source

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]

open access: yes, 2011
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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