Results 61 to 70 of about 1,683,867 (302)

Variability of non-Gaussian diffusion MRI and intravoxel incoherent motion (IVIM) measurements in the breast. [PDF]

open access: yesPLoS ONE, 2018
We prospectively examined the variability of non-Gaussian diffusion magnetic resonance imaging (MRI) and intravoxel incoherent motion (IVIM) measurements with different numbers of b-values and excitations in normal breast tissue and breast lesions ...
Mami Iima   +9 more
doaj   +1 more source

Diffusion Anisotropy and Tensor-valued Encoding

open access: yes, 2020
The study of diffusion anisotropy via diffusion NMR was pioneered 40 years ago in systems pertaining to the field of porous media. Since then, its combination with MRI has attracted overwhelming interest within the neuroscience community as a way to ...
Reymbaut, Alexis,, Lund University.
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

microTorch: A Software Package for Fast and Flexible Self-Supervised Diffusion MRI Model Fitting

open access: yesJournal of Open Research Software
The microTorch software package allows for the fast and flexible fitting of a wide range of multi-compartment microstructure models to diffusion magnetic resonance imaging (dMRI) data.
Snigdha Sen   +11 more
doaj   +1 more source

Diffusion MRI: what water tells us about the brain

open access: yesEMBO Molecular Medicine, 2014
Diffusion MRI has been used worldwide to produce images of brain tissue structure and connectivity, in the normal and diseased brain. Diffusion MRI has revolutionized the management of acute brain ischemia (stroke), saving life of many patients and ...
Denis Le Bihan
doaj   +1 more source

The assessment of cerebral white matter microstructure in cerebral small vessel disease based on the diffusion-weighted magnetic resonance imaging

open access: yesАнналы клинической и экспериментальной неврологии, 2020
Introduction. Multidimensional or biophysical modelling approaches are actively used to examine the complex microstructure of brain matter in diffusion-weighted MRI, where tissue structures are schematically simplified and divided into separate regions ...
Elena I. Kremneva   +3 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan   +14 more
wiley   +1 more source

MR scanner systems should be adequately characterized in diffusion-MRI of the breast. [PDF]

open access: yesPLoS ONE, 2014
Breast imaging represents a relatively recent and promising field of application of quantitative diffusion-MRI techniques. In view of the importance of guaranteeing and assessing its reliability in clinical as well as research settings, the aim of this ...
Marco Giannelli   +8 more
doaj   +1 more source

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