Results 61 to 70 of about 2,219,909 (313)

MR scanner systems should be adequately characterized in diffusion-MRI of the breast. [PDF]

open access: yesPLoS ONE, 2014
Breast imaging represents a relatively recent and promising field of application of quantitative diffusion-MRI techniques. In view of the importance of guaranteeing and assessing its reliability in clinical as well as research settings, the aim of this ...
Marco Giannelli   +8 more
doaj   +1 more source

Multiparametric magnetic resonance imaging of the prostate-a basic tutorial. [PDF]

open access: yes, 2017
Prostate cancer is the second most common cause of cancer related death in the United States and the most commonly diagnosed malignancy in men. In general, prostate cancer is slow growing, though there is a broad spectrum of disease that may be indolent,
Cabarrus, Miguel C   +1 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey   +17 more
wiley   +1 more source

The road to breast cancer screening with diffusion MRI

open access: yesFrontiers in Oncology, 2023
Breast cancer is the leading cause of cancer in women with a huge medical, social and economic impact. Mammography (MMG) has been the gold standard method until now because it is relatively inexpensive and widely available.
Mami Iima, Mami Iima, Denis Le Bihan
doaj   +1 more source

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao   +5 more
wiley   +1 more source

Comparison of MR cytometry methods in predicting immunohistochemical factor status and molecular subtypes of breast cancer

open access: yesRadiology and Oncology
First evaluation of the performance of MR cytometry incorporating transcytolemmal water exchange in predicting immunohistochemical factor status and molecular subtypes of breast cancer.
Wu Lei   +10 more
doaj   +1 more source

MRI‐cytometry: Mapping nonparametric cell size distributions using diffusion MRI

open access: yesMagnetic Resonance in Medicine, 2020
This report introduces and validates a new diffusion MRI‐based method, termed MRI‐cytometry, which can noninvasively map intravoxel, nonparametric cell size distributions in tissues.
Junzhong Xu   +10 more
semanticscholar   +1 more source

Moyamoya Disease and the Risk of Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo   +9 more
wiley   +1 more source

Joint estimation of relaxation and diffusion tissue parameters for prostate cancer with relaxation-VERDICT MRI

open access: yesScientific Reports, 2023
This work presents a biophysical model of diffusion and relaxation MRI for prostate called relaxation vascular, extracellular and restricted diffusion for cytometry in tumours (rVERDICT).
Marco Palombo   +10 more
doaj   +1 more source

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