Results 31 to 40 of about 173,790,028 (255)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Innovation diffusion process of higher education informatization based on Lotka-Volterra model.

open access: yesPLoS ONE
In order to quantify the diffusion speed, influence scope and change trend of educational informatization innovation in colleges and universities, this paper studies the diffusion process of educational informatization innovation in colleges and ...
Junjuan Liu, Peiling Yan
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Dynamical Innovation Diffusion Model with Fuzzy Coefficient and Its Application to Local Telephone Diffusion in China

open access: yesDiscrete Dynamics in Nature and Society, 2013
This paper studies the innovation diffusion problem with the affection of urbanization, proposing a dynamical innovation diffusion model with fuzzy coefficient, and uses the shifting rate of people from rural areas stepping into urban areas to show the ...
Zhigao Liao, Jiuping Xu, Liming Yao
doaj   +1 more source

Innovation and the Diffusion of Technology in Agriculture in Floodplains in the State of Amazonas

open access: yesRAC: Revista de Administração Contemporânea, 2019
There is a vast literature on innovation and diffusion of technology in Agribusiness. The dominant explanation of dissemination of innovations emphasizes processes involving information flows through a social system.
Jonas Fernando Petry   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Diffusion Efficiency of Innovation among EU Member States: A Data Envelopment Analysis

open access: yesEconomies, 2019
Innovation, in contemporary times, has been established as the lynchpin of growth and national competitive advantage among countries. Supranational and national resources have jointly combined to create sound innovation strategies and diffusion policies ...
Henry Junior Anderson, Jan Stejskal
doaj   +1 more source

Keberhasilan Difusi Inovasi Gagasan Social Enterprise dalam Pemberdayaan Masyarakat Islam: Studi Komunitas Kampung Marketer Purbalingga

open access: yesAt-turas: Jurnal Studi Keislaman, 2021
Diffusion of innovation is an important part in the process of da'wah and empowerment of Islamic society. This article describes the strategies and success factors for the diffusion of innovation in the Islamic community empowerment programs implemented ...
Wahanani Mawasti
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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