Results 31 to 40 of about 166,426,886 (289)
Transforming the practice of medicine through team science
Health Research Policy and Systems, 2020 Background The translation of biomedical research discoveries into clinical practice is marked by extended timelines (averaging 17 years) and multiple sequential process steps.
Jason H. Pitzen +7 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
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RisksAgainst the backdrop of China’s innovation-driven development strategy, innovation diffusion is a key stage through which firm-level innovation outcomes generate broader economic value.
Quan Li, Haodan Sun, Gaoya Song
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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Innovation diffusion process of higher education informatization based on Lotka-Volterra model.
PLoS ONEIn order to quantify the diffusion speed, influence scope and change trend of educational informatization innovation in colleges and universities, this paper studies the diffusion process of educational informatization innovation in colleges and ...
Junjuan Liu, Peiling Yan
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Discrete Dynamics in Nature and Society, 2013 This paper studies the innovation diffusion problem with the affection of urbanization, proposing a dynamical innovation diffusion model with fuzzy coefficient, and uses the shifting rate of people from rural areas stepping into urban areas to show the ...
Zhigao Liao, Jiuping Xu, Liming Yao
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Innovation and the Diffusion of Technology in Agriculture in Floodplains in the State of Amazonas
RAC: Revista de Administração Contemporânea, 2019 There is a vast literature on innovation and diffusion of technology in Agribusiness. The dominant explanation of dissemination of innovations emphasizes processes involving information flows through a social system.
Jonas Fernando Petry +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Diffusion Efficiency of Innovation among EU Member States: A Data Envelopment Analysis
Economies, 2019 Innovation, in contemporary times, has been established as the lynchpin of growth and national competitive advantage among countries. Supranational and national resources have jointly combined to create sound innovation strategies and diffusion policies ...
Henry Junior Anderson, Jan Stejskal
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