Results 111 to 120 of about 3,370,652 (304)
EPITHET: Positive Result After Reanalysis Using Baseline Diffusion-Weighted Imaging/Perfusion-Weighted Imaging Co-Registration
, 2011 Background and Purpose-The Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) was a prospective, randomized, double-blinded, placebo-controlled, phase II trial of alteplase between 3 and 6 hours after stroke onset.Kimber, T., Nagakane, Yoshinari, Levi, Christopher R, Levi, CR, Parsons , Mark W, Bladin, Christopher F, Brekenfeld, Caspar, Fink, J, Schultz, David W, Tress, B. M., Kimber , Thomas E, De Silva , Deidre A, Thomas E. Kimber, Levi, C. R., Kimber, TE, Muir, KW, Levi, C., Fink , John, Butcher, K., Leonid Churilov, John Fink, Christensen , Soren, Patricia M. Desmond, EPITHET Investigators,, Churilov, Leonid, Ma, H, Butcher, K. S., Desmond, PM, Tress, BM, Kimber, Thomas E, Muir, K., Keith W. Muir, Peeters, A, Muir, Keith W, P. Alan Barber, Mark W. Parsons, Davis, Stephen M, Fink, John, Desmond, P., Butcher, Kenneth S, Christensen, S., Donnan Geoffrey, A, Davis, S. M., Nagakane, Y, Tress, B., Brian M. Tress, Bladin , Christopher F, Yoshinari Nagakane, Barber, P Alan, Donnan, G. A., Christopher F. Bladin, Kimber, T. E., Henry Ma, Desmond , Patricia M, Davis, SM, De Silva, D., Schultz, D., Desmond, Patricia M, Nagakane, Y., Bladin, CF, Parsons, MW, Brekenfeld, C, De Silva, DA, EPITHET Investigators, Bladin, C. F., Desmond, P. M., Peeters, A., Barber, P. A., Christensen, Soren, Davis, S., Levi , Christopher R, Deidre A. De Silva, Barber, Peter, Geoffrey A. Donnan, Barber , P Alan, Stephen M. Davis, Caspar Brekenfeld, Andre Peeters, Christensen, S, Schultz , David W, Kenneth S. Butcher, De Silva, D. A., Butcher , Kenneth S, Parsons, M., Churilov , Leonid, Nagakane , Yoshinari, Peeters, Andre, Parsons, M. W., Donnan, Geoffrey A, Fink, J., Christopher R. Levi, Butcher, KS, Donnan, G., Schultz, D. W., Parsons, Mark W, Muir , Keith W, Ma, H., Donnan, GA, Muir, K.W., Churilov, L, Soren Christensen, De Silva Deidre, A, Ma , Henry, Churilov, L., Tress, Brian M, Ma, Henry, Bladin, C., Barber, P., Brekenfeld , Caspar, Brekenfeld, C., David W. Schultz, Schultz, DW +111 morecore +1 more sourceLong‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods
Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).Kathryn B. Holroyd, Tyler Hamby, Carlo Sacdalan, Somchai Sriplienchan, Pathariya Promensa, Luxenaree Poonpitak, Netsiri Dumrongpisutikul, Eugène Kroon, Sandhya Vasan, Robert Paul, Ferron O'Campo, Lydie Trautmann, Phillip Chan, Serena Spudich, on behalf of the RV254/SEARCH 010 Study Team, Julie Ake, Sandhya Vasan, Lydie Trautmann, Merlin Robb, Trevor Crowell, Donn Colby, Diane Bolton, Shelly Krebs, Leigh Ann Eller, Morgane Rolland, Rasmi Thomas, Dominic Paquin Proulx, Suteeraporn Pinyakorn, Tyler Hamby, Mark de Souza, Ellen Turk, Amber Moodley, Gerald Quarles, Jintanat Ananworanich, Denise Hsu, Victoria Polonis, Nelson Michael, Sheila Peel, COL Eric Garges, Alexandra Schuetz, Siriwat Akapirat, Bessara Nantapinit, Pornsuk Visudhiphan, Saowanit Getchalarat, Nampueng Churikanont, Sangsulee Thamakaison, Somchai Sriplienchan, Carlo Sacdalan, Pathariya Promsena, Luxe‐naree Poonpitak, Eugene Kroon, Nitiya Chomchey, Jintana Intasan, Varaporn Pothipala, Ferron Ocampo, Nittaya Phanuphak, Nipat Teeratakulpisan, Yuwaree Pichitchok, Anchalee Avihingsanon, Opass Putcharoen, Kiat Ruxrungtham, Thanyawee Puthanakit, Sopark Manasnayakorn, Phandee Watanaboonyongcharoen, Rungsun Rerknimitr, Irini Sereti, Daniel Douek, Eli Bortiz, Frank Maldarelli, Mary Kearney, Serena Spudich, Phillip Chan, Lishomwa Ndhlovu, Guinevere Li, Michael Corley, Victor Valcour, Peter Hunt, Jacob Estes, Afam Okoye, Jeff Lifson, Claire Deleage, Nicolas Chomont, Andres Finzi, Lyle McKinnon, Henrik Zetterberg, Robert Siliciano, Robert Paul, Julie Mannarino, Jonathan Li, John Mellors, Josh Cytkor, Dan Barouch, Michael Seaman, Boris Juelg, Alex Shalek, Timothy Schacker, Ashley Haase, Mario Stevenson, Wenjun Li, Arthur Kim, Sharon Lewin, Adam Carrico, Susana Valente, Fred Hutchinson, Josh Schiffer, Guido Ferrari, Beau Ances, Alberto Bosque, Katharine Bar, Killian Pohl, David Ho, Yaoxing Huang, Michael Busch, Mohamed Abdel‐Mohsen, Johanna Gostner, Brian Agan, Fatah Kashanchi, Greg Laird, Kathryn Holroyd +118 morewiley +1 more sourcePyogenic brain abscess with atypical features resembling glioblastoma in advanced MRI imaging
Radiology Case Reports, 2017 Differentiation between infectious and neoplastic brain processes is crucial for treatment planning. Advanced magnetic resonance imaging techniques, such as diffusion, perfusion, susceptibility weighted imaging, and magnetic resonance spectroscopy ...Arsany Hakim, MD, Markus Oertel, MD, Roland Wiest, MD +2 moredoaj +1 more sourceRe‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT
Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil +9 morewiley +1 more sourceArterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background/Objective
Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael +22 morewiley +1 more sourceThe Value of Susceptibility-Weighted Imaging (SWI) in Evaluating the Ischemic Penumbra of Patients with Acute Cerebral Ischemic Stroke
Neuropsychiatric Disease and Treatment, 2021 Yong-Ren Wang, Zhao-Sheng Li, Wei Huang, Hui-Qiang Yang, Bo Gao, Yu-Ting Chen Department of Radiology, Chinese Medical Hospital of Yiwu, Yiwu, 322000, People’s Republic of ChinaCorrespondence: Yong-Ren WangDepartment of Radiology, Chinese Medical ...Wang YR, Li ZS, Huang W, Yang HQ, Gao B, Chen YT +5 moredoaj