Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Addressing Ethical, Legal, and Social Issues on Artificial Intelligence Together With Patients' Perspectives: Prerequisites for Responsible Social Implementation in Endoscopy. [PDF]
Dig EndoscTsuji Y, Fujishiro M.
europepmc +1 more source
Tri‐WOB: A Bistability‐Driven Variable Stiffness Origami Structure for Soft Robotic Arms
Advanced Science, EarlyView.Inherent bistability in Waterbomb origami enables the Tri‐WOB to switch between compliant and stiff states. By stacking multiple modules, the robotic arm maintains stiffness without continuous energy input while achieving large contraction, free morphing, and load‐bearing/transportation capability.
Lingchen Kong, Yaoyao Fiona Zhao
wiley +1 more source
Interfacial Water Configurations: Evolution and Implications for Electrocatalysis
Advanced Science, EarlyView.A comprehensive and mechanistic understanding of how interfacial water structures govern reaction pathways. This review aims to bridge the gap between unraveling the intricate role of water structures and establishing robust design principles for advanced catalysts.
Aoqi Wang +7 more
wiley +1 more source
Epidermal growth factor receptor-targeted near-infrared photoimmunotherapy for malignant pleural mesothelioma. [PDF]
Lung CancerKano M +7 more
europepmc +1 more source
Advanced Science, EarlyView.A latent diffusion‐based framework is proposed for designing functionally graded metamaterials with perfect connectivity. By integrating vector‐quantized latent representations with mechanistic guidance, the framework enables accurate inverse design toward target elastic properties.
Jongbin Yu, Dosung Lee, Namjung Kim
wiley +1 more source
Three-dimensional computed tomography reconstruction of the gastroesophageal junction following hiatal hernia repair with Collis gastroplasty and fundoplication: a novel method to demonstrate postoperative morphology and better understand hiatal hernia recurrence. [PDF]
Arq Bras Cir DigLuna RA +7 more
europepmc +1 more source
Advanced Science, EarlyView.Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi +7 more
wiley +1 more source
"K" EY rules to improve learning skills in forth arm robotic platform. [PDF]
Arq Bras Cir DigBigolin AV, Cavazzola LT, Kalil AN.
europepmc +1 more source
Advanced Science, EarlyView.Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao +5 more
wiley +1 more source