Results 181 to 190 of about 1,654,137 (372)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Clinical application of pre-rehabilitation concept on comfort colonoscopy in Chinese elderly patients: a randomised controlled trial

BMC Gastroenterology
Background The concept of pre-rehabilitation has been clinically implemented across various surgical fields; however, studies investigating its application in colonoscopy remain limited. This study aimed to evaluate the effectiveness, safety, and patient
Lun Zhang, Xiaoling Lv, Qin Zhu, Jianying Zhou, Hanlei Huang, Yiqian Huang, Caijuan Si   +6 more
doaj   +1 more source

Fruit carotenoids affect the bioaccessibility and cellular uptake of ß-carotene from orange fleshed sweet potato [PDF]

, 2011
Context and motivation of the work: To fight against vitamin A deficiency in developing countries, consumption of orange fleshed sweet potato (OFSP) which contains high concentrations of beta-carotene (provitamin A) is currently promoted.
Borel, Patrick, Dhuique-Mayer, Claudie, Günata, Ziya, Poulaert, Marie   +3 more
core  

Simulated gastrointestinal digestion and storage stability of tomato waste encapsulates

, 2021
Slađana Stajčić, Jasna Čanadanović‐Brunet, Gordana Ćetković, Vesna Tumbas Šaponjac, Jelena Vulić, Vanja Šeregelj   +5 more
openalex   +2 more sources

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Machine learning and radiomics for segmentation and classification of adnexal masses on ultrasound

npj Precision Oncology
Ultrasound-based models exist to support the classification of adnexal masses but are subjective and rely upon ultrasound expertise. We aimed to develop an end-to-end machine learning (ML) model capable of automating the classification of adnexal masses.
Jennifer F. Barcroft, Kristofer Linton-Reid, Chiara Landolfo, Maya Al-Memar, Nina Parker, Chris Kyriacou, Maria Munaretto, Martina Fantauzzi, Nina Cooper, Joseph Yazbek, Nishat Bharwani, Sa Ra Lee, Ju Hee Kim, Dirk Timmerman, Joram Posma, Luca Savelli, Srdjan Saso, Eric O. Aboagye, Tom Bourne   +18 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

MAGqual: a stand-alone pipeline to assess the quality of metagenome-assembled genomes

Microbiome
Background Metagenomics, the whole genome sequencing of microbial communities, has provided insight into complex ecosystems. It has facilitated the discovery of novel microorganisms, explained community interactions and found applications in various ...
Annabel Cansdale, James P. J. Chong
doaj   +1 more source

The biologic digestion of garbage with sewage sludge [PDF]

, 1936
Bibliography: p.
Babbitt, Harold Eaton, Leland, Benn J., Whitley, Fenner H.   +2 more
core