Results 41 to 50 of about 244,982 (129)
The radical Pietist Johann Conrad Dippel was a self‐proclaimed adept – a maker of gold and the philosophers’ stone. He was also a magister of theology, a doctor of medicine, and a self‐taught chemist, who coinvented the pigment Prussian Blue together with Johann von Diesbach, became known for his animal pyrolysis oil, his wonder‐wound balm, his ...
Curt Wentrup
wiley +1 more source
In this study, a computational pipeline is developed to systematically evaluate the conformational stability, disulfide bond reduction state, and aggregation and degradation tendencies of an anticancer VHH‐Fc fusion antibody. Based on the mechanistic insights, antibody variants with enhanced stability and increased yield are successfully designed. This
Yuan Fang+10 more
wiley +1 more source
The anaerobic digestion technology has been in existence for centuries and its underlying theory established for decades. It is considered a useful technology for the generation of renewable energy, and provides means to alleviate problems associated ...
A. Anukam+3 more
semanticscholar +1 more source
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han+15 more
wiley +1 more source
Anti‐inflammatory macrophage‐derived exosomes modified with selfantigen peptides are developed to induce antigen‐specific immune tolerance. These exosomes demonstrate prophylactic effects in experimental autoimmune encephalomyelitis. Abstract Current treatments for autoimmune diseases often involve broad‐acting immunosuppressants, which carry risks ...
Qiaoyun Li+5 more
wiley +1 more source
Phenolic adhesive muscle extracellular matrix hydrogels with improved tissue adhesion, mechanical properties, and muscle‐specific cues are developed to treat muscle loss. These hydrogels facilitate muscle regeneration in disuse‐induced muscle atrophy and sarcopenia mouse models by generating enduring muscle‐like microenvironments for rejuvenating ...
Soojeong Choi+5 more
wiley +1 more source
Polyethylene (PE) microplastics retained in sewage sludge inevitably enter the anaerobic digestion system. To date, no information has been reported on the mechanisms of PE microplastics affecting anaerobic digestion of waste activated sludge (WAS). This
Wei Wei+4 more
semanticscholar +1 more source
A high‐efficiency, prevascularization‐free macroencapsulation system for the subcutaneous transplantation of pancreatic islets is developed. This novel system demonstrates excellent long‐term blood glucose control at the subcutaneous site, even with the transplantation of ≈250 IEQ of islets.
Seunggyu Jeon+5 more
wiley +1 more source
Human Placenta in Premodern Europe—a Cultural and Pharmaceutical Agent**
Abstract This paper was prompted by some striking similarities between both the ritual and the medical use of placenta in Ming China and in premodern Europe. Contrary to most accounts, which focus either on the rise of chemiatric medicine or on the growing interest in “exotic” substances, the seventeenth century in Europe also reveals a revived ...
Bettina Wahrig
wiley +1 more source
Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry
Enzymatic digestion for protein sequencing usually requires much time, and does not always result in high sequence coverage. Here we report the use of aqueous microdroplets to accelerate enzymatic reactions and, in particular, to improve protein ...
Xiaoqin Zhong, Hao Chen, R. Zare
semanticscholar +1 more source