Results 171 to 180 of about 2,631,756 (296)

Diagnostics of Digestive System Diseases in Cats

Bolesti probavnog sustava mačaka česta su pojava u svakodnevnoj veterinarskoj praksi. Neke od češćih bolesti probavnog sustava mačaka su akutna ili kronična upala gušterače, lipidoza jetre, kolangiohepatitis, upalna bolest crijeva, megakolon, ileus ...
Cindrić, Rina
core  

Understanding Liver and Digestive Diseases: A Paved Road to Improve Diagnosis, Management, and Treatment. [PDF]

Explor Dig Dis
Bergheim I, Cadranel JF, Chen JG, Ding WX, Eferl R, Garcia-Ruiz C, Jaeschke H, Kazerouni F, Lonardo A, Mann DA, Mendez-Sanchez N, Mokhtari C, Moshage H, Raggi C, Strnad P, Tirosh O, Zougmore HT, Fernandez-Checa JC.   +17 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Health-Related Quality of Life Changes in Patients with Digestive Cancers and Chronic Digestive Diseases: A Prospective, Multicenter Study. [PDF]

J Clin Med
Martín J, Larrea N, García Y, Bolinaga I, Perales A, Sarasqueta C, González-Pinto A, Quintana JM.   +7 more
europepmc   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Associations of digestive diseases exposure and lifestyle factors with Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Yang K, Zeng R, Zheng Y, Zhong S, Wang J, Yu X, Zhong H, Chen X, Shi Y, Lin F, Ye Q, Sun N, Cai G.   +12 more
europepmc   +1 more source

Mitochondrial SLC25A46 Rewires Fatty Acid Oxidation to Promote Cell Proliferation and Ferroptosis Evasion in Ovarian Cancer by Stabilizing CACT

Advanced Science, EarlyView.
Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao, Jiatao Hao, Xiaohong Zhang, Meiting Long, Yujing Feng, Xiaoyue Liu, Xuejian Li, Shujuan Liu, Xin Guo, Xiaohui Lv   +9 more
wiley   +1 more source

Noncanonical clock regulators control stress responses in digestive diseases. [PDF]

Trends Endocrinol Metab
Zhou D, López-Valiente RE, Mattar SG, Guan D.   +3 more
europepmc   +1 more source

Digestive Disease as an Economic Problem

Gastroenterology, 1967
Thomas P. Almy, Marvin H. Sleisenger
openaire   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source