Results 211 to 220 of about 2,631,756 (296)

Loop9 closure technique for mucosal defects after colorectal endoscopic submucosal dissection (with video)

Endoscopy International Open
Mayo Tanabe, Haruhiro Inoue, Yuto Shimamura, Akiko Toshimori, Marc Julius Hernandez Navarro, Yusuke Fujiyoshi, Mary Raina Angeli Fujiyoshi, Daijiro Shiomi, Yumi Kishi, Kei Ushikubo, Yohei Nishikawa, Manabu Onimaru, Takayoshi Ito, Naoyuki Uragami, Noboru Yokoyama   +14 more
doaj   +1 more source

Unveiling the potential of <i>Lactobacillus johnsonii</i> in digestive diseases: a comprehensive review. [PDF]

Front Microbiol
Zhou J, Ma S, Huang Z, Yao Q, Yu Z, Chen J, Yao L, Zhu L, Chen X.   +8 more
europepmc   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Water hardness and digestive diseases: a large-scale population-based prospective cohort study. [PDF]

Int J Surg
He Q, Sun M, Sun M, Huang J, Wang Q, Adamkiewicz G, Shen Y, Li L.   +7 more
europepmc   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Editorial: Microbiota homeostasis and metabolic reprogramming in cancer development and digestive diseases. [PDF]

Front Cell Dev Biol
Li K.
europepmc   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Uric acid influences the relationship between unsafe neighborhood and digestive diseases among middle-aged or older adults: a longitudinal cohort study from the China Health and Retirement Longitudinal Study (CHARLS). [PDF]

BMC Public Health
Du J, Yang S, Qu C, Cai L, Yuan X, Zhang J, Li X, Shen T.   +7 more
europepmc   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

REG/Reg family proteins: mediating gut microbiota homeostasis and implications in digestive diseases. [PDF]

Gut Microbes
Qi Z, Pang W, Zha X, Liu Y, Liu S, Xiao F, Wang X, Zhou J, Wang W, Liu X.   +9 more
europepmc   +1 more source