Results 201 to 210 of about 1,070,196 (253)

Effects of Fermented Longan Peel (<i>Dimocarpus longan</i>) on Growth Performance, Digestive Enzyme Activity, Intestinal Microstructure, Immune Response, and Gene Expression of Nile Tilapia (<i>Oreochromis niloticus</i>) Raised Under Biofloc System. [PDF]

Antioxidants (Basel)
Wannavijit S, Ninyamasiri P, Nonkrathok W, Tongsiri S, Seesuriyachan P, Phimolsiripol Y, Hoseinifar SH, Van Doan H, Paolucci M.   +8 more
europepmc   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Effects of Polystyrene Nanoplastics on Oxidative Stress, Blood Biochemistry, and Digestive Enzyme Activity in Goldfish (<i>Carassius auratus</i>). [PDF]

Toxics
Azarm-Karnagh S, Sattari M, Banaee M, Shirkavand Hadavand B, Falco F.   +4 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Influence of Coffee Roasting Degree from Four Mexican Regions on In Vitro Antioxidant Activity and Digestive Enzyme Inhibition and Its In Vivo Effects on Carbohydrate and Lipid Absorption. [PDF]

Int J Mol Sci
Gamboa-Gómez CI, Barragán-Zúñiga J, Herrera MD, Alongi M, Rocha-Guzmán NE, Herrera-Rocha KM, Dominguez D, Valles-Araiza KF, Anese M, Rodríguez-Morán M, Guerrero-Romero F.   +10 more
europepmc   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Comprehensive LC-ESI-HRMS/MS Profiling and Assessment of Texture, Predicted Glycaemic Index, Antioxidant Activity and Digestive Enzyme Inhibition of Gluten- and Lactose-Free Cookies Enriched with Pomegranate By-Products. [PDF]

Foods
Pino R, Tundis R, Sicari V, Mincione A, Gattuso A, La Torre C, Fazio A, Piacente S, Masullo M, Cerulli A, Loizzo MR.   +10 more
europepmc   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Effects of Dietary Cinnamaldehyde Supplementation on Growth Performance, Serum Antioxidant Capacity, Intestinal Digestive Enzyme Activities, Morphology, and Caecal Microbiota in Meat Rabbits. [PDF]

Animals (Basel)
Chen D, Lan Y, He Y, Gao C, Jiang B, Xie X.   +5 more
europepmc   +1 more source

A three-dimensional and multivariate statistical analysis of serine-hydrolases active sites.

, 2012
EBERT, CYNTHIA, FOSCATO, MARCO, GARDOSSI, Lucia, FERRARIO, VALERIO   +3 more
core