Results 61 to 70 of about 1,070,196 (253)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Digestive enzymes of postweaned greenlip abalone (Haliotis laevigata) are influenced by water temperatures and dietary protein levels

Aquaculture, Fish and Fisheries
Digestive enzyme activities are known to fluctuate in abalone grown under different environmental conditions however the effects of different dietary regimes are less clear.
Matthew S. Bansemer, Michael J. Salini, Jian G. Qin, James O. Harris, Gordon S. Howarth, David A. J. Stone   +5 more
doaj   +1 more source

Effects of dietary Phaffia rhodozyma on the growth, immunity, antioxidant activity, and digestive tract microbiota of juvenile Strongylocentrotus intermedius

Aquaculture Reports
Strongylocentrotus intermedius is a commercially valuable aquaculture species. Phaffia rhodozyma, a yeast rich in astaxanthin and β-glucans, has immune-enhancing and antioxidant properties in aquatic animals; however, its effects on S. intermedius remain
Yuchun Lu, Teng Teng, Yiwen Lan, Zi-Ao Ren, Yu Du, Feng Liu   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Histological and molecular characterization of the digestive system of early weaned juveniles of Arapaima sp. reared in a recirculating aquaculture system.

PLoS ONE
Arapaima spp., the world's largest scaled freshwater fish, native to the Amazon and Essequibo river basins, are valued in aquaculture for their rapid growth and ornamental appeal.
Maria J Darias, Guillain Estivals, Karl B Andree, Christian Fernández-Méndez, Roger Bazán, Chantal Cahu, Enric Gisbert, Diana Castro-Ruiz   +7 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Digestive Enzymatic Activity Profiles and Larval Growth Performance of Barramundi, Lates calcarifer (Bloch, 1790), From Indonesian and Australian Broodstocks

Biotropika: Journal of Tropical Biology
Barramundi fish is one of the most important aquaculture commodities, with cultivation challenges closely related to its survival and growth. There is still a lack of information on digestive enzymatic activity profiles and larval growth, and the use of ...
Gigih Setia Wibawa, Haryanti Haryanti, Nia Kurniawan   +2 more
doaj   +1 more source

Enzyme activities of digestive enzyme supplements and purified enzymes.

, 2015
The content of one capsule of supplement was weighed and the enzyme activities measured as specified in Materials and Methods. In the case of HUT, activity per capsule ((capsule content in mg) * (specific activity in HUT/mg)) matches with the product ...
Chantal Christis (748028), Drew Smith (748031), Yvonne Kooy-Winkelaar (748029), Luppo Edens (748030), Frits Koning (4899), George Janssen (748027), Peter van Veelen (235080)   +6 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source