Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater +13 more
wiley +1 more source
<i>Bacillus subtilis</i> G01: A Multifunctional Agent with Broad-Spectrum Antimicrobial Activity and Digestive Enzymes for Sustainable Agriculture and Animal Husbandry. [PDF]
Yan Y +6 more
europepmc +1 more source
Effects of dietary resveratrol supplementation on digestive enzymes activities and serum biochemistry of rainbow trout (Oncorhynchus mykiss). [PDF]
Afzali-Kordmahalleh A, Meshkini S.
europepmc +1 more source
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang +10 more
wiley +1 more source
Effects of dietary <i>Chlorella vulgaris</i> and cinnamon oil on growth performance, gut morphology, digestive enzymes, and intestinal gene expression in broilers. [PDF]
Kewan A +8 more
europepmc +1 more source
Influence of artificial diets on biological characteristics and digestive enzymes of Coccinella septempunctata L. [PDF]
Cheng Y, Yu Y, Li W, Li F.
europepmc +1 more source
ELABELA Targets Mitochondria to Modulate Heart Development
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang +22 more
wiley +1 more source
Diverse Misfolding Mutant Digestive Enzymes Cause Chronic Pancreatitis Through Common Pathways. [PDF]
Wilhelm SJ +7 more
europepmc +1 more source
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
Ziziphus spina-christi (L.) Leaf Extract Improves Growth, Feed Utilization, Digestive Enzymes and Blood Metabolites in Broiler Chickens. [PDF]
Reda FM +8 more
europepmc +1 more source

