Results 141 to 150 of about 22,831,370 (389)
BMC GastroenterologyBackground Metabolic dysfunction-associated fatty liver disease (MAFLD) has become the most prevalent chronic liver condition in adolescents. The triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, has shown promise in adult MAFLD
Yigui Zou +8 more
doaj +1 more source
An international study of young people's drawings of what is inside themselves [PDF]
, 2002 What do young people know of what is inside them and how does this knowledge depend on their culture? In this study a cross-sectional approach was used involving a total of 586 pupils from 11 different countries.
Reiss, Michael, Tunnicliffe, Sue Dale
core
Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms [PDF]
, 2019 Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable ...
Abessa, D. M. S. +5 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
An Economic Analysis of a Dairy Anaerobic Digestion (A.D.) System: Will Dairy Producers Invest in A.D. Technology to Reduce Potential Litigation Suits? [PDF]
In many areas of the United States, dairy and livestock farmers are facing lawsuits due to a variety of externalities, such as odor and other forms of non-point source pollution, caused by Confined animal feeding operations (CAFO's).
Davis, Brandon L.
core +1 more source
Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]
, 2016 The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico +5 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
PCR-based molecular characterization of Blastocystis hominis subtypes in southwest of Iran
Journal of Infection and Public Health, 2018 Blastocystis hominis is the most common intestinal parasite found in humans and many other hosts. Pathogenicity of Blastocystis sp. remains controversial and it has been suggested that it may be associated with certain subtypes of organism.
Shahram Khademvatan +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Frontiers in ImmunologyBackgroundImmune checkpoint inhibitors (ICIs) represent a paradigm shift in the development of cancer therapy. However, the improved efficacy of ICIs remains to be further investigated.
Tianrui Kuang +11 more
doaj +1 more source