Results 151 to 160 of about 22,831,370 (389)

Clustering of Molecular Alterations in Gastroesophageal Carcinomas

open access: yesNeoplasia: An International Journal for Oncology Research, 2004
Gene expression levels are regulated at many levels. Integration of genome-wide analyses for the study of DNA and RNA provides a unique tool to detect genetic alterations in the cancer genome.
Natalie Koon   +6 more
doaj   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

open access: yesFEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Walking a Versatile Exercise [PDF]

open access: yes, 2008
Editorial discussing about the benefits of walking, which is a versatile exercise for osteoarthritis, general body conditioning and also for various other systems of the body like cardio-vascular system, digestive system, respiratory system ...
Singh U
core  

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari belonging to glycoside hydrolase family 10

open access: yesFEBS Open Bio, EarlyView.
Fervidibacter sacchari is a member of the bacterial phylum Armatimonadota, only a few of which have been cultivated. It is a hyperthermophilic polysaccharide degradation specialist. We show that a secreted enzyme, Fsa02490Xyn, is an endoxylanase belonging to glycoside hydrolase family 10.
Nicole Torosian   +10 more
wiley   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

The Relationship between Serum Zinc Level and Liver Elastrography Using Fibroscan in Non-Alcoholic Fatty Liver Patients

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2018
BACKGROUND AND OBJECTIVE: Zinc is one of the essential elements for many vital functions of the body, including regulation of gene expression, anti-inflammatory and antioxidant activity, protein and nucleic acids metabolism.
E Hajiani   +3 more
doaj  

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