Results 61 to 70 of about 100,617 (251)

Experiencia en el Hospital Universitario San Vicente de Paúl sobre el manejo quirúrgico de los pacientes con ano imperforado Experience in the management of patients with imperforated anus at San Vicente de Paul Hospital

open access: yesRevista Colombiana de Cirugía, 2005
Con el propósito de definir las complicaciones tempranas de la corrección quirúrgica del ano imperforado alto y bajo en el Hospital Universitario San Vicente de Paúl de la ciudad de Medellín, Colombia, se estudiaron 128 casos intervenidos quirúrgicamente
María Elena Arango   +2 more
doaj  

Factors of immunodeficiency in children with trisomy 21 (Down syndrome): a modern paradigm of immune and non-immune mechanisms

open access: yesZdorovʹe Rebenka, 2018
Down syndrome is the most common genetic disorder. Children with trisomy 21 often suffer from severe, prolonged respiratory infections, which is an immune system defect.
O.L. Logvinova
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Gut dysmotility in functional gastrointestinal disorders. Potential for therapeutic adjustment in terms of clinical case management

open access: yesМедицинский совет, 2020
Gastrointestinal motility disorders can be a leading pathogenetic factor contributing to the development of many common gastroenterological diseases. Motor disorders can be a pathogenetic mechanism of development of both organic pathology (developmental ...
I. G. Pakhomova
doaj   +1 more source

UY-NET: A Two-Stage Network to Improve the Result of Detection in Colonoscopy Images

open access: yesApplied Sciences, 2023
The human digestive system is susceptible to various viruses and bacteria, which can lead to the development of lesions, disorders, and even cancer. According to statistics, colorectal cancer has been a leading cause of death in Taiwan for years.
Cheng-Si He   +3 more
doaj   +1 more source

PEDOT‐Based Eutectogel Electrode Arrays for Enhanced High‐Resolution Electrogastrography: Fabrication, Stability, and Wearable Performance

open access: yesAdvanced Functional Materials, EarlyView.
Here, we present a high‐density PEDOT eutectogel electrode array for enhanced body surface gastric mapping. Silver electrodes are blade‐coated onto flexible substrates, followed by electrogelation of PEDOT:PSS and the deposition of a PEDOT:LS eutectogel.
Christopher Slaughter   +8 more
wiley   +1 more source

Hypertrophic pyloric stenosis masked by kidney failure in a male infant with a contiguous gene deletion syndrome at Xp22.31 involving the steroid sulfatase gene: case report

open access: yesItalian Journal of Pediatrics, 2022
Background Contiguous gene deletion syndrome at Xp22.3 resulting in nullisomy in males or Turner syndrome patients typically encompasses the steroid sulfatase gene (STS) and contiguously located other genes expanding the phenotype.
Ingrid Anne Mandy Schierz   +8 more
doaj   +1 more source

Reprogramming Tumor Cell Death via Processing Natural Drug to Carbon Dots Overcomes Collagen Barrier and Activates Antitumor Immunity

open access: yesAdvanced Functional Materials, EarlyView.
A traditional Chinese medicine‐derived carbon dots nanoplatform reprograms tumor cell death from apoptosis to necroptosis, dismantling therapy‐induced collagen barriers and promoting immunogenic death. pH‐responsive hydrogel assembled from carbon dots for localized delivery, this strategy suppresses primary tumors and metastasis, offering a new ...
Zekun Yan   +11 more
wiley   +1 more source

Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. [PDF]

open access: yes, 2017
BACKGROUND: Gastrointestinal tract (GIT) involvement is a common cause of debilitating symptoms in patients with systemic sclerosis (SSc). There are no disease modifying therapies for this condition and the treatment remains symptomatic, largely owing to
Abraham   +105 more
core   +2 more sources

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch   +13 more
wiley   +1 more source

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