Results 131 to 140 of about 19,447,195 (247)

Survival Outcomes in Older Adults with Axial Spondyloarthritis and Concomitant Cancer

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman, Mei Li, Xiudong Lei, Hui Zhao, Juan I. Ruiz, Sharon H. Giordano, Alexis R. Ogdie, Maria E. Suarez‐Almazor   +7 more
wiley   +1 more source

TGFB1/CXCL5 axis regulation by LCN2 overexpression: a promising strategy to inhibit colorectal cancer metastasis and enhance prognosis

Frontiers in Immunology
BackgroundDistant metastasis remains a major reason for the high recurrence and mortality of colorectal cancer (CRC). However, the underlying molecular mechanisms driving metastasis in CRC remain poorly understood.
Xiaotian Song, Xiaotian Song, Shuai Xu, Shuai Xu, Dan Song, Juan Wang, Bin Bai, Yanxin An, Bin Yang, Shiqi Wang, Qingchuan Zhao, Pengfei Yu   +11 more
doaj   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Are idiopathic and chagasic achalasia two different diseases?

, 2004
Although Chagas' disease esophagopaty and idiopathic (primary) achalasia share several similarities, however, some differences between the two diseases have been noticed. To evaluate if treatment options and their results can be accepted universally, the
Del Grande, J. C., Herbella, FAM, Oliveira, DRCF   +2 more
core   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

The Main Symptoms and Syndromes in Diseases of the Digestive System

, 2016
The article presents the main clinical symptoms and syndromes that occur in various diseases of the abdominal cavity. Both widely known and rare symptoms of gastroenterological dise­ases are presented.
О.M. Kovalenko, I.N. Kononov, M.V. Chalyi   +2 more
core   +1 more source

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

Advanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer, H. Mutlu, C. Charmette, E. Randrianaridera, Z. Adaidi, R. Hedna, L. Pieuchot, I. Pluvy, K. Anselme, N. Couturier, J. P. Mericq, A. Ponche, I. Brigaud   +12 more
wiley   +1 more source

Diagnostics of Digestive System Diseases in Cats

Bolesti probavnog sustava mačaka česta su pojava u svakodnevnoj veterinarskoj praksi. Neke od češćih bolesti probavnog sustava mačaka su akutna ili kronična upala gušterače, lipidoza jetre, kolangiohepatitis, upalna bolest crijeva, megakolon, ileus ...
Cindrić, Rina
core  

Urgent revascularization of a liver allograft with a saphenous vein interposition graft between the hepatic artery and the recipient splenic artery after late hepatic artery

, 2005
Digestive Diseases and Sciences, Vol. 50, No. 6 (June 2005), pp. 1177–1180 ( C 2005)Hepatic artery thrombosis (HAT) after liver transplantation is a severe complication which may lead to graft infarction and subsequent graft loss. It complicates 2–12%
Işık, Burak, Söğütlü, Gökhan, Yılmaz, Sezai, Kırımlıoğlu, Vedat, Ara, Cengiz, Battaloğlu, Bektaş, Yılmaz, Mehmet, Kırımlıoğlu, Hale   +7 more
core   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source