Results 81 to 90 of about 29,018 (264)
ENDOSCOPY IN TIME CAN BE A LIFE SAVER: OUR UPPER ENDOSCOPY RESULTS
Objectives: Endoscopy is the best diagnostic test for the diseases in upper digestive system. In addition to diagnosis, endoscopy is also useful in treatment of specific conditions.
Mustafa Sit +2 more
doaj
Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin +10 more
wiley +1 more source
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang +7 more
wiley +1 more source
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
Until few years ago, radiological methods were widely used for the examination and investigation of the digestive tract. Today, wireless capsule endoscopy represents an innovative, noninvasive, effective solution that does not imply a risk of irradiation.
Roxana Andreea BĂLAN +2 more
doaj
Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao +3 more
wiley +1 more source
Outcomes of surgical versus conservative treatment in pediatric median arcuate ligament syndrome
Abstract Objectives Median arcuate ligament syndrome (MALS) involves compression of the celiac artery and presents with gastrointestinal symptoms. We evaluated outcomes after surgical versus conservative management in pediatric MALS. Methods We reviewed charts of symptomatic patients aged 7–21 years diagnosed by ultrasound and/or computed tomography ...
Mohamad Abi Nassif +9 more
wiley +1 more source
Abstract Objective Pediatric aerodigestive and upper gastrointestinal (UGI) motility disorders are common and may be associated with compromised nutritional status and decreased quality of life. Traditional dietary recommendations for aerodigestive and UGI motility disorders have been rudimentary and largely based upon experience and common sense ...
Khalil El‐Chammas +8 more
wiley +1 more source
ABSTRACT The Global Burden of Disease (GBD) database provides essential primary data for public health research. However, its complexity and diversity pose challenges for conducting advanced secondary analyses. To address these challenges, we developed easyGBDR, an innovative integrated R toolkit designed to facilitate the secondary analysis of GBD ...
Yingying Fang +9 more
wiley +1 more source
Update in the diagnosis and treatment of upper gastrointestinal bleeding
During the last years, multiple factors have conditioned the incidence of non-varicose upper gastrointestinal bleeding, causing the interest of specialists in its study. As a result, there are many ways of diagnosis and modalities for its treatment.
Roberto Cobiellas-Rodríguez +2 more
doaj

