Results 91 to 100 of about 45,320 (289)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia   +4 more
wiley   +1 more source

Intra-abdominal hemorrhage due to a short gastric artery injury following esophagogastroduodenoscopy and colonoscopy: a case report [PDF]

open access: yesJournal of Acute Care Surgery
This case describes a rare but serious complication of endoscopic procedures, highlighting the importance of vigilance in acute care. A 79-year-old man who underwent simultaneous esophagogastroduodenoscopy and colonoscopy developed hemoperitoneum caused ...
Yook Kim, Younghoon Sul
doaj   +1 more source

Implementing Wireless Capsule Endoscopy WCE In Digestive System Diagnostics [PDF]

open access: yes, 2014
The purpose of this research is to discuss the revolutionary endoscopy method WCE that would enhance the diagnostic accuracy and reliability level. Additionally, a comparison has been made with other currently in practice endoscopy methods to single out ...
Bach, Christian, Ghunaim, Hussam
core  

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

open access: yesiNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao   +3 more
wiley   +1 more source

Rapamycin and Chloroquine Modulate Insulin Resistance and Hepatic Steatosis in a High-Fat/High-Cholesterol Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease Mouse Model

open access: yesDiabetes, Metabolic Syndrome and Obesity
Qi Liu,1,* Qian Du,2,* Xiaolu Yuan,3 Ting Zhang,3 Jiajing Li,3 Jingyu Xu,4 Rui Xie2 1Department of Gastroenterology, Zhejiang Provincial People’s Hospital Bijie Hospital, Bijie, Guizhou, People’s Republic of China; 2Department of ...
Liu Q   +6 more
doaj  

Comparisons of Celiac Disease and Non-Celiac Gluten Sensitivity [PDF]

open access: yes, 2020
Celiac disease (CD) and non-celiac gluten sensitivity (NCGS) are often confused or grouped together due to their commonalities. However, this is careless behavior because there are clinically significant differences between the two diseases. Similarities
Thomas, Victoria
core   +1 more source

Ultrasound–triggered tumor‐selective nitric oxide release enhances tumor penetration of antibody–conjugated nanomedicine

open access: yesInterdisciplinary Medicine, EarlyView.
Ultrasound‐triggered nitric oxide release from S‐nitrosated hyaluronic acid (HA‐SNO) induces tumor vasodilation and disrupts the vascular barrier, potently enhancing the intratumoral penetration of antibody‐conjugated nanomedicines. Abstract The tumor vascular barrier restricts the penetration of antibody‐conjugated nanomedicine, severely limiting its ...
Xiaodong Wang   +4 more
wiley   +1 more source

Oral Cryptococcosis due to Naganishia diffluens in a Patient With Thalassemia: A Case Report and a Literature Review

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh   +13 more
wiley   +1 more source

Degree of swallowing impairment in the elderly: clinical and instrumental assessment

open access: yesBrazilian Journal of Otorhinolaryngology
Objective: To classifying the degree of swallowing impairment in the elderly, comparing clinical and instrumental assessment. Methods: This is a cross-sectional study with quantitative and qualitative analysis of clinical and instrumental assessment of ...
Tatiane Totta Salgado   +5 more
doaj   +1 more source

Acute esophageal necrosis, black esophagus: a case report

open access: yesIatreia, 2016
Acute esophageal necrosis, or black esophagus, is a rare syndrome affecting sick elderly patients, with high mortality rate. Its clinical expression is gastrointestinal bleeding.
Ramírez-Quintero, Juan David   +2 more
doaj   +1 more source

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