Results 91 to 100 of about 17,458,229 (270)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

Clinicopathological Spectrum of Gastroenteropancreatic Neuroendocrine Tumours- A Series of Ten Cases [PDF]

open access: yesNational Journal of Laboratory Medicine
Neuroendocrine neoplasms are unique, as many of them are associated with secretory properties and specific syndromes of uncontrolled hormone hypersecretion.
Muktanjalee Deka   +7 more
doaj   +1 more source

Second neoplasms after oesophageal cancer

open access: yes, 2007
The authors considered the incidence of second neoplasms among 1,672 oesophageal cancers diagnosed between 1974 and 2004 in the Cancer Registries of the Swiss Cantons of Vaud and Neuchatel, and followed-up to 2004.
Randimbison, Lalao   +4 more
core   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

THE ANALYSIS OF THE POPULATION MORTALITY OF THE YAMAL-NENETS AUTONOMOUS DISTRICT FOR THE PERIOD OF 1993-2016

open access: yesКубанский научный медицинский вестник, 2018
Aim. This study was designed for the determination of the priority directions of the reduction of the population mortality of the Yamalo-Nenets autonomous district and the estimation of the place of death from certain major groups of death causes in ...
E. A. Sukhova
doaj   +1 more source

Silicone Breast Implants as a Model System for Understanding Polymer Permeation in Soft Materials In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
Silicone breast implants are presented as a model system for understanding polymer permeation in vivo. Rather than representing material failure, “gel bleed” emerges from solution–diffusion transport‐mediated. By integrating polymer architecture, physicochemical transport, and biointerfacial processes, this review provides a unified framework that ...
D. Bouyer   +12 more
wiley   +1 more source

Mucinous cystic neoplasms of the pancreas

open access: yes, 2010
Definition and classification of Mucinous cystic neoplasms. A cyst-forming epithelial neoplasm that usually does not communicate with the pancreatic ductal system, and is composed of columnar, mucin-producing epithelium associated with ovarian-type
Hruban RH   +3 more
core   +1 more source

Causality between insulin use and malignant tumors of the digestive system: a two-sample mendelian randomized study

open access: yesBMC Cancer
Background Existing cohort studies show no association between insulin use and cancers of the digestive system, while numerous meta-analyses suggest that insulin use increases the risk of digestive system tumours.
DengZhuo Chen   +6 more
doaj   +1 more source

Radiomics and artificial intelligence-based prediction of tumor response in digestive system neoplasm: a systematic review and meta-analysis

open access: yesFrontiers in Medicine
BackgroundRadiomics and artificial intelligence (AI) are progressively gaining recognition for predicting tumor response, recurrence, and prognosis in gastrointestinal tumors.
Songxia Yu   +4 more
doaj   +1 more source

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