Results 101 to 110 of about 17,458,229 (270)

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Benign Biliary Tumors and Precursor Neoplasms: An Updated Clinicopathological and Molecular Review Based on the 2026 WHO Classification

open access: yesBiomedicines
Benign biliary tumors and precursor neoplasms of the biliary tract are a heterogeneous group of uncommon neoplasms with significant clinical and diagnostic implications.
Joon Hyuk Choi
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

open access: yesAdvanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz   +5 more
wiley   +1 more source

Retinol and tocopherol content in primary and metastatic digestive neoplasms.

open access: yes, 2003
Purpose: Recent controlled and randomized trials in patients at risk of lung and upper or lower digestive-tract cancer have produced conflicting and uncertain results regarding the protective role of liposoluble vitamin supplementation, mainly when ...
CASALGRANDI, Giovanna   +4 more
core  

Iterative Selection of DNA Nanostructures for Cellular Uptake

open access: yesAdvanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar   +4 more
wiley   +1 more source

Advances in Cancer Vaccines for Digestive System Cancers: A Systematic Analysis of Clinical Trials [PDF]

open access: yes
Jianing Li,1 Peili Wang2 1Graduate School, Heilongjiang University of Chinese Medicine, Harbin, People’s Republic of China; 2Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of ChinaCorrespondence: Peili Wang, Email ...
Li J, Wang P
core  

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

open access: yesAdvanced Materials, EarlyView.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song   +8 more
wiley   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

open access: yesAdvanced Materials Technologies, EarlyView.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib   +10 more
wiley   +1 more source

Mucinous Neoplasms

open access: yes, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
D'ONOFRIO, Mirko   +15 more
core   +1 more source

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