Results 151 to 160 of about 45,406 (222)

Prospects for fistula technologies in the study of digestion and metabolism in birds. [PDF]

Front Physiol
Vertiprakhov VG, Zaitsev SY.
europepmc   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source

Development of a Robotic Training Curriculum for Visceral and Gastrointestinal Surgical Trainees: An International Delphi Study. [PDF]

United European Gastroenterol J
Fadel MG, Walshaw J, Yiasemidou M, Boal M, Pecchini F, Elhadi M, Massey LH, Carrano FM, Fehervari M, Walsh CM, Boshier PR, Eckhoff J, Buckle P, ERSC Study Group, Gisbertz SS, Bouvy N, Arezzo A, Perretta S, Nickel F, Khan J, Hanna GB, Seeliger B, Antoniou SA, Fuchs HF, Francis NK, Kontovounisios C.   +25 more
europepmc   +2 more sources

Robotic-assisted hepatopancreatoduodenectomy for intraductal papillary neoplasm of the bile duct: future approach for minimally invasive biliary surgery. [PDF]

Hepatobiliary Surg Nutr
Lan Z, Lan T, Chen W, Huang K, Zhang J, Mao W, Meng B, Wang J, Zhong Z, Lu T, Song R, Xu B, Zhu H, Wen Z.   +13 more
europepmc   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

COVID-19 on Elective Surgery Outcomes in a Brazilian Tertiary Hospital: A Retrospective Cohort Study. [PDF]

Med Sci Monit
Ferreira DP, Bolognani CV, Fernandes LAS, de Morais MSF, Souza LLS, Bolognani MV, Madureira GA, Santana LA, Amorim FF.   +8 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Designing a national network of pancreas units: the Italian model for high-quality pancreatic cancer care. [PDF]

Updates Surg
Alfieri S, Quero G, Tondolo V, Balzano G, Cardone A, Conzo G, Fabbri C, Ferrari V, Frulloni L, Gruttadauria S, Ianelli E, Maiello E, Menghi R, Milella M, Reni M, Salvia R, Spada C, De Bella MT, Tarantino I, Tortora G, Valsecchi F, Vincenti L, Vistoli F, Boggi U.   +23 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Future impacts of colectomy healthcare pathways on quality of care in bundled payment experiments, a national retrospective cohort in France. [PDF]

PLoS One
Sanchez MA, Mercier G, Clément MC, Ortega-Deballon P, Sanchez S, Quantin C.   +5 more
europepmc   +1 more source