Results 81 to 90 of about 134,814 (305)
Background: In Brazil, there has been a significant increase in obesity rates in all age groups. Data from 2017 show that obesity affects 19% of the population.
Antoninho José Tonatto-Filho+4 more
semanticscholar +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima+6 more
wiley +1 more source
Reconstrução abdominal tardia sem tensão após laparostomia: uma nova técnica
OBJETIVO: A reconstrução abdominal tardia após laparostomia é sempre um procedimento desafiador para o cirurgião devido à necessidade de se corrigir um grande defeito na parede abdominal anterior, o que habitualmente demanda a lise de extensas aderências
Marcos Campos W. Reis+4 more
doaj +1 more source
Injuries of the retrohepatic inferior vena cava and the liver [PDF]
Beckground. Injuries of the retrohepatic inferior vena cava, and the liver have mortality rate up to 71-78%. We presented a patient with combined injury of the retrohepatic inferior vena cava, liver, craniocerebral and thoracic traumas, inflicted in a ...
Koprivica Radenko+3 more
doaj +1 more source
Risk factor identification and contribution to surgery-specific surgical site infection
Background: To identify common risk factors for the future occurrence of SSI across digestive system surgical procedures, thoracic surgery and orthopaedic procedures and quantify what the marginal contribution of explaining the future occurrence of SSI
(Magnus) Johan Magnus van Niekerk+5 more
semanticscholar +1 more source
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Meshless treatment of open inguinal hernia repair: a prospective study
OBJECTIVE: To evaluate two types of meshless open inguinal repair and to evaluate the recurrence rate. METHODS: We operated on sequentially 98 men and 15 women with 144 unilateral or bilateral inguinal hernias between December 1988 and April 2007.
Paulo Kassab+5 more
doaj +1 more source