Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley +1 more source
A generative deep neural network for pan-digestive tract cancer survival analysis. [PDF]
Xu L +8 more
europepmc +1 more source
Early‐Life Clinical Factors Shape Cerebellar Structure in Preterm‐Born Children
ABSTRACT Objective Preterm birth alters typical brain development due to complex exposures related to neonatal illness, pain management, and brain injury. Despite an increased understanding of neonatal brain injury on developmental outcomes, the association of cerebellar maturation with school‐age motor and cognitive function remains incompletely ...
Victoria Rapos +6 more
wiley +1 more source
Deep learning-based fusion of nuclear segmentation features for microsatellite instability and tumor mutational burden prediction in digestive tract cancers: a multicenter validation study. [PDF]
Zhang Y +7 more
europepmc +1 more source
Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming +14 more
wiley +1 more source
Application of artificial intelligence in the diagnosis of malignant digestive tract tumors: focusing on opportunities and challenges in endoscopy and pathology. [PDF]
Gao Y +15 more
europepmc +1 more source
Sequentially bidirectional gastrovascular flows in intricately branched digestive tract of planocerid flatworms. [PDF]
Hsu PC, Chang YH, Chiu YN, Jie WB.
europepmc +1 more source
Influence of the Origin, Feeding Status, and <i>Trypanosoma cruzi</i> Infection in the Microbial Composition of the Digestive Tract of <i>Triatoma pallidipennis</i>. [PDF]
Gutiérrez-Millán E +3 more
europepmc +1 more source
Endoscopic retrograde cholangiopancreatography consultation after digestive tract reconstruction and risk factors for complications. [PDF]
Cheng Y, Feng J, Chen X, Lin J, Wang H.
europepmc +1 more source

