Results 61 to 70 of about 1,098,872 (313)

Interaction of Vibrio spp. with the Inner Surface of the Digestive Tract of Penaeus monodon

open access: yesPLoS ONE, 2015
Several species of Vibrio are the causative agent of gastroenteritis in humans. In aquaculture, Vibrio harveyi (Vh) and V. parahaemolyticus (Vp) have long been considered as shrimp pathogens in freshwater, brackish and marine environments.
Wipasiri Soonthornchai   +4 more
semanticscholar   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

open access: yesAdvanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian   +9 more
wiley   +1 more source

Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

open access: yesGenome Biology, 2012
BackgroundTo understand the relationship between our bacterial microbiome and health, it is essential to define the microbiome in the absence of disease. The digestive tract includes diverse habitats and hosts the human body's greatest bacterial density.
N. Segata   +7 more
semanticscholar   +1 more source

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han   +16 more
wiley   +1 more source

Microbiota from Litopenaeus vannamei: digestive tract microbial community of Pacific white shrimp (Litopenaeus vannamei)

open access: yesSpringerPlus, 2014
Bacteria capable of producing different extracellular enzymes of potential relevance in digestive processes were isolated from the stomach, hepatopancreas and intestine of Pacific white shrimp Litopenaeus vannamei.
Jaqueline Tuyub Tzuc   +4 more
semanticscholar   +1 more source

Studies on the glycopeptide in digestive tracts

open access: yesSEIBUTSU BUTSURI KAGAKU, 1977
Glycopeptide was isolated from tryptic digests of different parts of digestive tract, including esophagus, small intestine, large intestine and rectum of man and animals. Analysis was carried out by cellulose acetate strip electrophoresis, followed by staining with PAS (Schiff) and alcian blue.The results have been discussed and summarized as follows.1.
Shigeki Shichijo   +2 more
openaire   +4 more sources

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

open access: yesAdvanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui   +6 more
wiley   +1 more source

PRDM16 Reduces Cellular Senescence by Upregulating GSTM1

open access: yesAdvanced Science, EarlyView.
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan   +7 more
wiley   +1 more source

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