Results 41 to 50 of about 20,242 (263)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

Advanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi, Ebrahim Norouzi, Kostiantyn Hubaiev, Jörg Waitelonis, Harald Sack   +4 more
wiley   +1 more source

THE METHODOLOGY OF CIRCUIT CONSTRUCTION OF THE ANALOG VALUE CONVERTER IN THE TIMEFRAME

Измерение, мониторинг, управление, контроль, 2023
Background. Most modern digital voltmeters use an analog-to-digital converter (ADC) of the time-pulse type with two-stage integration, which takes place in two stages – integration and counting.
Mikhail A. Vatutin, Vitaliy P. Efimov, Evgeny V. Bormatov, Anton V. Zubkov   +3 more
doaj   +1 more source

Evaluating Energy Absorption Performance of Filled Lattice Structures

Advanced Engineering Materials, EarlyView.
Maximum stress must be considered to robustly evaluate energy absorber designs. This approach was applied to compare all types of absorbers in a single Ashby diagram and determine the utility of filling lattice voids with a second material. High‐performance fillers can improve the performance of lattices that are limited by buckling or catastrophic ...
Christian Bonney, William P. King, Iwona Jasiuk   +2 more
wiley   +1 more source

DESIGN AND IMPLELMENTATION A PC BASED SYSTEM FOR CIRCUIT TESTING

Journal of Engineering, 2008
This thesis deals with design and implementation of PC based control unit for testing systems. The design of the system involves mainly the hardware circuits, and software.
ZAID ALI SALMAN, SARKOUT N. ABDULLA
doaj   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source

IMPLEMENTATION OF AN INTEGRATING ANALOG-DIGITAL CONVERTER WITH INTERMEDIATE PULSE LATESTIMATION MODULATION

Известия высших учебных заведений. Поволжский регион:Технические науки, 2020
Bachground. The technological breakthrough in the field of integrated electronics provides the production of sensor equipment with high metrological characteristics, expansion of their dynamic range of conversion, which, in turn, makes improving ...
V. N. Ashanin, A. A. Korotkov
doaj   +1 more source

A 0.5-V Fully Synthesizable SAR ADC for On-Chip Distributed Waveform Monitors

IEEE Access, 2019
This paper presents a fully synthesizable successive-approximation-register (SAR) analog-to-digital converter (ADC) for on-chip distributed waveform monitoring in a low-power system-on-chip (SoC).
Jun-Eun Park, Young-Ha Hwang, Deog-Kyoon Jeong   +2 more
doaj   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source