Results 41 to 50 of about 114,229,974 (287)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

A Low-Power Analog-to-Digital Converter [PDF]

open access: yes, 1964
Low-power analog-to-digital converter for digital voltage ...
Beck, C. W., Fryer, T. B.
core  

Extrapolating Analog-to-Digital Converter [PDF]

open access: yes, 2005
We propose a new type of oversampled analog-to-digital converter. It uses digital extrapolators to predict the analog signal before it is converted, and a coarse quantizer to convert the prediction error.
Yang, Zheng   +3 more
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

A Novel Compressing Analog-to-Digital Converter [PDF]

open access: yes, 2005
Analog-to-digital converters form the backbone of many real world systems. A compression and expansion (companding) capability is a useful tool to increase the signal-to-noise ratio of many of these applications.
Lauritzen, Keir Christian
core   +1 more source

50 YEARS OF INTEGRATING ANALOG-TO-DIGITAL CONVERTERS

open access: yesИзмерение, мониторинг, управление, контроль
Background. This article examines the fifty-year history of the theoretical development and refinement ofone of the most common classes of analog-to-digital converters, whose distinguishing feature is the use of a closed-loopstructure with integrators in
Boris V. Chuvykin, Irina A. Dolgova
doaj   +1 more source

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