Results 31 to 40 of about 10,941,453 (300)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Much of the early work on information theory was directed towards the study of the transmission of telegraph signals. These theoretical treatments lend themselves to descriptions of signals as digital phenomena they are much less convenient for dealing ...
Monk, John
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
A digital demodulator for converting pulse code modulated data from phase shift key (PSK) to non return to zero (NRZ) and to biphase data is described. The demodulator is composed of standard integrated logic circuits.
Shull, T. A.
core +1 more source
Digital Current-Control Schemes [PDF]
The paper is about comparing the performance of digital signal processor-based current controllers for three-phase active power filters. The wide use of nonlinear loads, such as front-end rectifiers connected to the power distribution systems for dc ...
Bojoi, Iustin Radu +3 more
core +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The power relationship between adults and children in the West is shifting. Factors of age and life experience are becoming counterbalanced by children’s affinity for burgeoning developments in digital technology, where skills developed in online ...
Williams, Peter.
core +3 more sources
Digital technology might lead to the extinction of criminal rehabilitation. In the digital era, criminal history records that were expunged by the state remain widely available through commercial vendors (data brokers) who sell this information to ...
Haber, Eldar
core +1 more source

