Results 61 to 70 of about 42,899,390 (303)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

JOURNALISM IN THE DIGITAL AGE - CHALLENGES AND SOLUTIONS FOR TRAINING WORK

open access: yesTạp chí Khoa học
The vigorous development of the Fourth Industrial Revolution has brought humanity into the digital age. Journalism and journalism training in Vietnam are facing many new problems; advantages and opportunities are intertwined with difficulties and ...
Vu Thi Phuong Le
doaj   +1 more source

Wheel Out the Digital Dark Age Klaxon!

open access: yes, 2022
Wheel Out the Digital Dark Age Klaxon, performed by the Digital Dark Age Crew. Written and produced by Marinus Nullbyte for the Digital Dark Age Crew, on the occasion of World Digital Preservation Day 2022.
van der Knijff, Johan
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Chicago Summer Institute 2012 - News in the Digital Age

open access: yes, 2011
Assignment where students examine the changes and growth of a Wikipedia story step by step.News in the Digital Age -- lecture13final.pptx Written Assignment: You Make the Decision -- email-assignment-prompt.pdf Emails for "Written Assignment: You Make ...
Stony Brook University. School of Journalism. Center for News Literacy.
core   +1 more source

Science in the digital age [PDF]

open access: yesNature, 2010
The goals of science have not changed since the early days of the Lindau meeting, yet the way they are pursued has.
openaire   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Diagnosing Qur’ānic Precepts on Wealth Creation in Digital Age

open access: yesInvest Journal of Sharia & Economic Law
This study examines how Islamic economic principles can provide guidance for ethical wealth creation, protection, and distribution in the rapidly evolving digital economy, particularly in the face of cybercrime and financial scams.
Sidiq Uthman Okanlawon   +2 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Bridging the age-based digital divide

open access: yes, 2015
An increasing reliance on digital technology in one’s everyday life necessitates the development of digital literacy skills to enable one’s continued participation in the Internet information-age.
Tuffley, David, Antonio, Amy
core   +1 more source

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