Results 81 to 90 of about 3,071,017 (311)

Impact of Digital Technology on Library Resource Sharing: Revisiting LABELNET in the Digital Age [PDF]

open access: yes, 2006
The digital environment has facilitated resource sharing by breaking the time and distance barriers to efficient document delivery. However, for the librarians, this phenomenon has brought more challenging technical and technological issues demanding ...
Jaswal, Bushra Almas
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Local Trade:Supporting Local Economic Resilience in the Digital Age [PDF]

open access: yes, 2012
This paper discusses the importance of economic resilience in times of financial turmoil and presents the preliminary results of a study on a new approach to supporting regional and local economies by incentivising locally beneficial consuming and ...
Balis, Gerasimos
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

A közszolgálati média alkotmányos helyzete, problémái a posztkommunista korszakban – a magyarországi tapasztalat

open access: yesSymbolon, 2015
The Constitutional Status of Public Media and its Problems in the Post-Communist Era: The Hungarian Experience The lecture analyzes the changes in the functions of public broadcasting within the digital era.
László Majtényi
doaj  

Sickness unto Death in the Age of 24/7: Wolfgang Herrndorf's Arbeit und Struktur

open access: yesStudies in 20th & 21st Century Literature, 2016
How does one die in the digital age? In exploring this question, this article juxtaposes Jonathan Crary’s critique of the contemporary and Wolfgang Herrndorf’s Arbeit und Struktur —a blog in which the German author documented his three-year battle ...
Lilla Balint
doaj   +1 more source

Team to Market (T2M): Creating High Performance Teams in the Digital Age [PDF]

open access: yes, 2020
1. Teams are the essential means of product or service delivery and the fundamental building blocks of modern organisations. An effective team can produce results far outperforming a collection of even the most talented individuals when team members ...
Li, F.
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Leading schools in the digital age: A clash of cultures [PDF]

open access: yes, 2008
A cultural gap is widening in English secondary schools: between a twentieth-century ethos of institutional provision and the twenty-first century expectations and digital lifestyles of school students. Perhaps disaffected by traditional teaching methods
Williams, Peter
core   +1 more source

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