Results 41 to 50 of about 36,482,451 (268)

Exploring the Potential of Exosomal Biomarkers in Mild Traumatic Brain Injury and Post-Concussion Syndrome: A Systematic Review

, 2023
Background: Alongside their long-term effects, post-concussion syndrome (PCS) and mild traumatic brain injuries (mTBI) are significant public health concerns.
Sidra Jabeen, Alin Ciobica, Vasile Burlui, Alin Iordache, Ioannis Mavroudis, Laura Romila, Ioana Miruna Balmus   +6 more
core   +1 more source

Exosomes as a Source of Biomarkers for Gastrointestinal Cancers [PDF]

, 2023
Exosomes are small, lipid-bilayer bound extracellular vesicles of 40–160 nanometers in size that carry important information for intercellular communication.
Farshid Dayyani, Dayyani, Farshid, Ostowari, Arsha, Yu, Jingjing, Maheswari Senthil, Hughes, Christopher CW, Christopher C. W. Hughes, Gonda, Amber, Arsha Ostowari, Jingjing Yu, Mashayekhi, Kiarash, Yu, Jingjing,; Ostowari, Arsha,; Gonda, Amber,; Mashayekhi, Kiarash,; Dayyani, Farshid,; Hughes, Christopher CW,; Senthil, Maheswari,, Senthil, Maheswari, Amber Gonda, Kiarash Mashayekhi   +14 more
core   +1 more source

A Novel Method for Tracking Neck Motions Using a Skin-Conformable Wireless Accelerometer: A Pilot Study

Digital Biomarkers
Introduction: Cervical spine disease is a leading cause of pain and disability. Degenerative conditions of the spine can result in neurologic compression of the cervical spinal cord or nerve roots and may be surgically treated with an anterior cervical ...
Le Huang, Keum San Chun, Lian Yu, Jong Yoon Lee, Alan Soetikno, Hope Chen, Hyoyoung Jeong, Joshua Barrett, Knute Martell, Youn Kang, Alpesh A Patel, Shuai Xu   +11 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Concurrent Validity of Inertially Sensed Measures during Voluntary Body Sway in Silence and while Exposed to a Rhythmic Acoustic Stimulus: A Pilot Study

Digital Biomarkers, 2021
Introduction: The effect of rhythmic acoustic stimuli on body sway is of increasing interest due to their positive contribution when training or restoring the control of movement.
Analina Emmanouil, Elissavet Rousanoglou, Anastasia Georgaki, Konstantinos Boudolos   +3 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Potential Impact of Preoperative Circulating Biomarkers on Individual Escalating/de-Escalating Strategies in Early Breast Cancer

, 2022
The research on non-invasive circulating biomarkers to guide clinical decision is in wide expansion, including the earliest disease settings. Several new intensification/de-intensification strategies are approaching clinical practice, personalizing the ...
Caterina Gianni, Michela Palleschi, Marita Mariotti, Ugo De Giorgi, Chiara Casadei, Samanta Sarti, Sara Bleve, Filippo Merloni, Marianna Sirico, Lorenzo Cecconetto, Giandomenico Di Menna   +10 more
core   +1 more source

Developing Smartphone-Based Objective Assessments of Physical Function in Rheumatoid Arthritis Patients: The PARADE Study

Digital Biomarkers, 2020
Background: Digital biomarkers that measure physical activity and mobility are of great interest in the assessment of chronic diseases such as rheumatoid arthritis, as it provides insights on patients’ quality of life that can be reliably compared across
Valentin Hamy, Luis Garcia-Gancedo, Andrew Pollard, Anniek Myatt, Jingshu Liu, Andrew Howland, Philip Beineke, Emilia Quattrocchi, Rachel Williams, Michelle Crouthamel   +9 more
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Development and Assessment of an Artificial Intelligence-Based Tool for Ptosis Measurement in Adult Myasthenia Gravis Patients Using Selfie Video Clips Recorded on Smartphones

Digital Biomarkers, 2023
Introduction: Myasthenia gravis (MG) is a rare autoimmune disease characterized by muscle weakness and fatigue. Ptosis (eyelid drooping) occurs due to fatigue of the muscles for eyelid elevation and is one symptom widely used by patients and healthcare ...
Meelis Lootus, Lulu Beatson, Lucas Atwood, Theo Bourdais, Sandra Steyaert, Chethan Sarabu, Zeenia Framroze, Harriet Dickinson, Jean-Christophe Steels, Emily Lewis, Nirav R. Shah, Francesca Rinaldo   +11 more
doaj   +1 more source