Results 51 to 60 of about 3,004,176 (304)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Digital collection in digital libraries
Journal of Information Processing and Management, 2004 昨今，インターネット経由でWebページを検索し，入手したい情報にアクセスする機会がますます増えており，日常的な人々の情報入手法にもなっている。本記事では，Web上でアクセスできる図書館のWebページで見られるデジタルコレクションについて，国立図書館では，米国議会図書館，英国図書館，オーストラリア国立図書館，カナダ国立図書館，大学図書館では，ハーバード大学図書館，スタンフォード大学図書館，ミシガン大学図書館，カリフォルニア大学バークレー校図書館，ワシントン州立大学図書館の現状を調べた。デジタルコレクションを大別して，1）ボーンデジタル資料 2）デジタルフォーマット化した資料 3）Web情報とし，それぞれについて上記図書館のデジタルコレクションの現状を展望した。また ...
openaire +2 more sources
Building the Glasgow Digital Library and its components [PDF]
, 2002 Describes the co-operative project to build a digital library by for and about the city of Glasgow. The library is built round a number of smaller projects which allowed participants to gain experience in building and managing digital ...
Law, Derek
core
The University Digital Library as a Center for Increasing the Digital Competences of Students [PDF]
, 2019 This paper aims to outline the advantages of increasing the quality of education at the University by describing some important organizational approaches and methodological guidelines for the development of digital competences among students.
Shopova, T. (Tatiana)
core +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Digital Guardianship: Innovative Strategies in Preserving Armenian’s Epigraphic Legacy
HeritageIn the face of geopolitical threats in Artsakh, the preservation of Armenia’s epigraphic heritage has become a mission of both historical and cultural urgency.
Hamest Tamrazyan, Gayane Hovhannisyan
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
RECUPERACIÓN DE IMÁGENES EN LA WEB: SISTEMA PROTOTIPO BASADO EN CONTENIDO Y MANEJO DE CALIDAD
Revista Ingenierías Universidad de Medellín, 2007 El presente artículo muestra una revisión de las investigaciones realizadas acerca de la recuperación de imágenes en colecciones digitales en la web, basado en su contenido y en el manejo de la calidad de la información.
Bell Manrique Losada +1 more
doaj
, 2015 Hello readers! The summer at Special collections is flying by and next week will already be my last week here as the Diane Werley Smith intern ’73. Though the weeks are winding down, we still are busy as bees here in Special Collections.
Fox, Avery N.
core +1 more source