Results 31 to 40 of about 38,518,564 (300)
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Creating a Digital Commons [PDF]
, 2006 The phrase information commons refers to our shared knowledge base. Heather Morrison presents examples of the commons in action, ranging from open access and open source scholarly resources to the blogosphere. The concept of sampling in music is discussed, and applied to librarianship.
Charbonneau, Olivier, Morrison, Heather
openaire +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Case studies (Swinburne Commons)
, 2016 Swinburne Commons is the centralised service for the management and distribution of digital media at Swinburne University. This video describes three digital media projects at Swinburne that we have been involved with: 1) EndNote tutorials; 2) MathsCasts
Swinburne Commons
core +1 more source
Digital Libraries and the Common Digital Space of Mathematical Knowledge
, 2021 We present the results of the development of a range of semantic services for the integrated management of electronic scientific collections. The goals of these developments are the formation of a unified digital space of mathematical knowledge, as well as information support for research activities in the field of mathematics and computer science ...
Alexander Elizarov, Evgeny Lipachev
openaire +2 more sources
HELIN Library Consortium LORI Grant Statewide Digital Repository Project for Rhode Island -- New Commons Consulting Proposal [PDF]
, 2014 Narrative and budget submitted by Robert Leaver of New Commons on the scope of work to be provided by New Commons to support the development of the RI Digital Repository and by the Reckoner Group to develop the prototype and website for this ...
New Commons, Leaver, Robert
core
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source