Results 141 to 150 of about 35,521,183 (298)

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

DIGITAL TRAINING TEACHER COMPETENCIES

Ra Ximhai, 2013
Currently we could say that in education internationally, nationally and locally, is the “fashion” and also a need to talk about teaching skills, digital skills, project work, learning to learn in schools of all levels, as it is in this case the high ...
Jesús Arturo Regalado Sandoval
doaj  

Digital transformation and the accounting education design dilemma: balancing today's vs. tomorrow's digital competency requirements

Frontiers in Education
The curricula digital transformation imperative refers to the urgent need for educators to ensure curricula cultivate graduates' knowledge of digital technologies and their ability to use new digital or digitally enhanced work tools, both for today's ...
Richard Busulwa, Wahed Waheduzzaman, Nandana Pathiranage, Kwang-Jing Yii   +3 more
doaj   +1 more source

Evaluating digital competencies for allied health professionals in the United Kingdom. [PDF]

Digit Health, 2023
Lee G, Caton E, Knight A.
europepmc   +1 more source

Defining data librarianship: a survey of competencies, skills, and training

, 2018
Federer Lisa, 2018, « Defining data librarianship: a survey of competencies, skills, and training », Journal of the Medical Library Association, 2018, vol. 106, no 3, p. 294‑303. doi: http://dx.doi.org/10.5195/jmla.2018.306 Objectives Many librarians are
Digital library
core  

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Teachers' AI digital competencies and twenty-first century skills in the post-pandemic world. [PDF]

Educ Technol Res Dev, 2023
Ng DTK, Leung JKL, Su J, Ng RCW, Chu SKW.   +4 more
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Transferring Healthcare Professional's Digital Competencies to the Workplace and Patients: A Pilot Study. [PDF]

Int J Environ Res Public Health, 2022
Navarro Martínez O, Igual García J, Traver Salcedo V.   +2 more
europepmc   +1 more source