Results 91 to 100 of about 1,385,411 (314)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Web application for assisting non-dermatology physicians in learning and managing patients with common cutaneous adverse drug reactions: a multicenter randomized controlled trial

Annals of Medicine
Background Cutaneous adverse drug reactions (CADRs) remain a challenge for non-dermatologists. Medical-related applications to assist in learning about and managing patients with CADRs are scarce.
Kannattha Chaisriya, Weeratian Tawanwongsri, Dichitchai Mettarikanon, Nuchsara Ameentranon, Chime Eden, Mathat Inthongpan, Sasipaka Sindhusen   +6 more
doaj   +1 more source

Clustering Using Boosted Constrained k-Means Algorithm

Frontiers in Robotics and AI, 2018
This article proposes a constrained clustering algorithm with competitive performance and less computation time to the state-of-the-art methods, which consists of a constrained k-means algorithm enhanced by the boosting principle.
Masayuki Okabe, Seiji Yamada
doaj   +1 more source

Building blocks for adaptable image search in digital libraries [PDF]

, 2014
: With the availability of easy and inexpensive methods to create and store images in digital formats, the visual information preserved and shared electronically has grown dramatically.
Springmann, Michael
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Knowledge management policies on digital content of libraries [PDF]

, 2005
We analyze the use of the digital content of non-profit libraries, such as, national and academic, worldwide, as expressed through the restrictions of intellectual property and the knowledge management policies.
Kapidakis, Sarantos, Koulouris, Alexandros   +1 more
core  

Sustainable Archiving and Storage Management of Audiovisual Digital Assets [PDF]

, 2008
With the advent of end-to-end tapeless production and distribution, the concept of what it means to archive audiovisual content is being challenged. The traditional role of the archive as a repository for material after broadcast is changing as a result ...
Lowe, R., Addis, Matthew, Norlund, Charlotte, Zlatev, Zlatko, Beales, R., Addis, M., Middleton, Lee, Zlatev, Z., Norlund, C., Beales, Richard, Lowe, Richard   +10 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The role of a digital librarian in the management of digital information systems (DIS) [PDF]

, 2000
Stresses that the multimedia nature of the next generation of digital libraries requires the digital librarians (DL) to be essentially a type of specialist librarian who has to manage and organize the digital library, handle the specialized tasks of ...
Sreenivasulu, V., Sreenivasulu, V
core  

Content

, 2015
DAFTAR ISIImplementasi Content-Based Retrieval Pada Perpustakaan Digital Berbasis Open Source Menggunakan Apache Lucene David Pages: 1-13Perancangan Sistem Kendali Otomatik Proses Pengolahan Limbah Cair Tahu Berbasis Mikrokontroler AT89S52Barita Bram ...
., Content
core   +1 more source