Results 141 to 150 of about 2,776,337 (305)

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa   +6 more
wiley   +1 more source

HERITRACE: A User-Friendly Semantic Data Editor with Change Tracking and Provenance Management for Cultural Heritage Institutions [PDF]

open access: yesarXiv
HERITRACE is a data editor designed for galleries, libraries, archives and museums, aimed at simplifying data curation while enabling non-technical domain experts to manage data intuitively without losing its semantic integrity. While the semantic nature of RDF can pose a barrier to data curation due to its complexity, HERITRACE conceals this intricacy
arxiv  

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

Social curation: collective participation in the curation of digital-virtual museum environments

open access: gold, 2022
Lucinéia da Silva Batista   +2 more
openalex   +2 more sources

Digital Gatekeepers: Google's Role in Curating Hashtags and Subreddits [PDF]

open access: yesProceedings of the 63rd Annual Meeting of the Association for Computational Linguistics 2025
Search engines play a crucial role as digital gatekeepers, shaping the visibility of Web and social media content through algorithmic curation. This study investigates how search engines like Google selectively promotes or suppresses certain hashtags and subreddits, impacting the information users encounter.
arxiv  

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

Facets of Digital Curation in the postcustodial paradigm: collective and social curation

open access: hybrid, 2022
Lucinéia da Silva Batista   +1 more
openalex   +1 more source

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

open access: yesAdvanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li   +16 more
wiley   +1 more source

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