Results 171 to 180 of about 505,707 (282)

Optimizing Territorial Healthcare Networks with a Capacity-Constrained Hub-And-Spoke Allocation Algorithm: The Province of L'Aquila Case Study. [PDF]

Healthcare (Basel)
Trebbi E, Barlattani T, Bologna A, Tognaccini L, Sili A, Di Martino G, Stan C, Odio C, Staniscia T, Pacitti F, Romano F.   +10 more
europepmc   +1 more source

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

Advanced Science, EarlyView.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He, Jing Li, Tian Guan, Yifei Ma, Zimo Zhao, Yanxia Wang, Hongjing Chen, Yingming Xu, Shuang Ge, Yexing Zhang, Yizhi Wang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Qingxia Hou, Shuyan Zhao, Xiaoqin Wang, Lili Ma, Peizhen Hu, Qiang Huang, Zihan Wang, Zhiyuan Shen, Junru Cheng, Siqi Zeng, Jiurun Chen, Zhen Song, Chao He, Zhe Wang, Yonghong He   +28 more
wiley   +1 more source

Use of Artificial Intelligence in Public Health Education for Pandemic Preparedness and Response. [PDF]

Ann Glob Health
Souza ECSG, Dos Santos Junior AG, Félix AMS, Borges JPA, de Oliveira LB, Carneiro LM, de Sousa AFL.   +6 more
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Absence of bladder cancer cells in surgical smoke from robot-assisted radical cystectomy: a prospective study. [PDF]

Front Urol
Shibamori K, Hashimoto K, Okabe K, Maehana T, Shindo T, Kyoda Y, Kobayashi K, Tanaka T, Takahashi S, Masumori N.   +9 more
europepmc   +1 more source

CD28‐Targeted Enzyme‐Responsive Conformation‐Switching Peptide Self‐Assembly for Selective T‐Cell Acute Lymphoblastic Leukemia (T‐ALL) Therapy

Advanced Science, EarlyView.
We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li, Ziyu Jia, Dekun Li, Zhi‐Wen Hu, Yinghao Ding, Shengyi Zhang, Shengkun Tuo, Zhimou Yang, Huisheng Fu, Ling Wang, Man‐Di Wang   +10 more
wiley   +1 more source

Deploying medical AI in low-resource settings: a scoping review of challenges and strategies. [PDF]

Front Digit Health
Al-Ganad A, Al-Shahdhi A, Al-Dhaifi O, Hajeb E, Hajeb H, Al-Motarreb A.   +5 more
europepmc   +1 more source

Hierarchical MXene/ZnO Nanorods: WO3/CNT Trilayer Coatings on Cotton for High‐Performance Multifunctional Wearable Fabrics

Advanced Science, EarlyView.
xx xx. ABSTRACT Fabric‐based wearable electronics are gaining increasing attention owing to their flexibility, breathability, biocompatibility, and seamless integration into clothing. However, most existing studies rely primarily on metallic or carbon‐based conductive materials.
Thirumalaisamy Suryaprabha, Chunghyeon Choi, Sujith Lal, Min‐Young Seo, Tae‐Wook Kim, Ergang Wang, Byungil Hwang   +6 more
wiley   +1 more source

Relationship between digital health literacy and self-assessment of health among older adults in Xuzhou City: based on the mediating effect of health self-management. [PDF]

Front Public Health
Qin Z, Shen H, Xu Y, Zhang H, Li X, Zhao Z, Li Y, Huang W.   +7 more
europepmc   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source