Results 31 to 40 of about 382,957 (312)

Media Digitization and Preservation Initiative: A Case Study

open access: yesInternational Journal of Digital Curation, 2018
Since its creation nearly a decade ago, the Digital Curation Centre (DCC) Curation Lifecycle Model has become the quintessential framework for understanding digital curation.
Devan Ray Donaldson   +6 more
doaj   +1 more source

The Collaboration and Application of Digital Content Curation in the University Archives

open access: yesTūzī yǔ dàng’àn xuékān, 2018
Digital content curation refers to the process of concentrating, extracting, insighting, mashing and serializing digital resources based on the theme through a screening mechanism, and presenting high-quality content with a single or combined method ...
Ching-Fei Huang, Chih-Ming Chen
doaj   +1 more source

Curadoria digital e preservação digital: cruzamentos conceituais [PDF]

open access: yes, 2016
The digital curation and digital preservation have as object of interest the maintenance of digital information over time. In the scientific literature, they have close definitions, however, digital curation is presented as a natural evolution of the ...
Santos, Thayse Natália Cantanhede
core   +4 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The Copyrights Chain in the Digital Curation Process

open access: yesInternational Journal of Digital Curation
The internet era, open access movement, image sharing platforms, and mainly the rise of artificial intelligence (AI) emphasise the importance of providing moderated access and licences for the reuse of collections by memory institutes as a key step in ...
Keren Barner
doaj   +1 more source

Digital Curation as a Core Competency in Current Learning and Literacy: A Higher Education Perspective

open access: yesInternational Review of Research in Open and Distributed Learning, 2016
Digital curation may be regarded as a core competency in higher education since it contributes to establishing a sense of metaliteracy (an essential requirement for optimally functioning in a modern media environment) among students.
Leona M. Ungerer
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Extracting, Transforming and Archiving Scientific Data [PDF]

open access: yes, 2011
It is becoming common to archive research datasets that are not only large but also numerous. In addition, their corresponding metadata and the software required to analyse or display them need to be archived. Yet the manual curation of research data can
Lemire, Daniel, Vellino, Andre
core   +1 more source

Curating the digital

open access: yesCHI '14 Extended Abstracts on Human Factors in Computing Systems, 2014
This workshop intends to use the key strength of the CHI Community; research linked to practice, to design an Art Catalog for CHI. The workshop will start with an examination of current research in curating interactive art. The outcomes of the first phase of the workshop will then feed into Design Charrette exercises that will involve prototyping an ...
England, D   +7 more
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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