Results 51 to 60 of about 239,611 (339)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

TRADITIONAL CRYPTOCURRENCIES AND FIAT-BACKED DIGITAL CURRENCIES [PDF]

open access: yesChallenges of the Knowledge Society, 2021
The digital payments space saw vigorous investment activity during 2020 and there have been a plethora of announcements about account based Central Bank Digital Currencies.
Serghei MĂRGULESCU, Elena MĂRGULESCU
doaj   +2 more sources

The Impact of Central Bank Digital Currency on Rural Revitalization: An Empirical Analysis of Data from 284 Cities in China

open access: yesSAGE Open
As legal tender created using advanced digital technology, Central Bank Digital Currency provides new opportunities for driving rural revitalization. This paper empirically assesses the impact of Central Bank Digital Currency on rural revitalization by ...
Muchen Li, Shining Guo, Qianyi Zhang
doaj   +1 more source

FOREIGN EXCHANGE MARKETS AND OPERATIONS IN THE CONTEXT OF DIGITALIZATION

open access: yesВестник Северо-Кавказского федерального университета, 2022
The article discusses the theoretical foundations of the functioning of currency markets. Classification of types of currency transactions according to the legislation of the Russian Federation is given.
J. Konopleva, O. Pakova, K. Gavrilov
doaj  

(WP 2013-09) Virtual Currency and the Financial System: The Case of Bitcoin [PDF]

open access: yes, 2013
Technological development and the increased use of the internet have led to the proliferation of virtual communities. Some of these communities have created and circulated their own currency for exchanging goods and services.
Chowdhury, Abdur, Mendelson, Barry K.
core   +1 more source

Сryptocurrency and Internet of Things: Problems of Implementation and Realization [PDF]

open access: yes, 2018
IoT (Internet of Things) requires the implementation of digital encryption of information, transaction support and recording of all events for security. It can provide cryptocurrencies protocols with adding an additional possibility of payments.
Kopytko, Vasyl   +4 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Foreign experience in defining the legal framework, implementation and research of digital currencies

open access: yesУченые записки Российской академии предпринимательства
Digital currencies of national banks are becoming more and more tightly integrated into the modern reality. Many countries around the world are at different stages of creating, piloting and implementing digital currencies. Undoubtedly, digital currencies
E. M. Musatov   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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