Results 81 to 90 of about 5,768,137 (296)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Surface Deformation of Xiamen, China Measured by Time-Series InSAR

Sensors
Due to its unique geographical location and rapid urbanization, Xiamen is particularly susceptible to geological disasters. This study employs 80 Sentinel-1A SAR images covering Xiamen spanning from May 2017 to December 2023 for comprehensive dynamic ...
Yuanrong He, Zhiheng Qian, Bingning Chen, Weijie Yang, Panlin Hao   +4 more
doaj   +1 more source

Digital data processing of images.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974
Digital data processing was investigated to perform image processing. Image smoothing and restoration were explored and promising results obtained. The use of the computer, not only as a data management device, but as an important tool to render quantitative information, was illustrated by lung function determination.
Lotter, M.G., Minnaar, P.C., Verster, F., Kleynhans, P.H.T., van Aswegen, A., van Heerden, P.D.R., le Roux, P.L.M   +6 more
openaire   +3 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Integrating TV/digital data spectrograph system [PDF]

A 25-mm vidicon camera was previously modified to allow operation in an integration mode for low-light-level astronomical work. The camera was then mated to a low-dispersion spectrograph for obtaining spectral information in the 400 to 750 nm range.
Brown, R. M., Duncan, B. J., Fay, T. D., Miller, E. R., Neely, P. L., Wamsteker, W.   +5 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Author Correction: First validation of a model-based hepatic percutaneous microwave ablation planning on a clinical dataset

Scientific Reports, 2023
Bruno Frackowiak, Vincent Van den Bosch, Zoi Tokoutsi, Marco Baragona, Martijn de Greef, Aaldert Elevelt, Peter Isfort   +6 more
doaj   +1 more source

On the Generation of Synthetic Invoices for Training Machine Learning Models

IEEE Access
Currently, the problem of generating synthetic financial documents is particularly acute. Extending recent research on the topic, we present an enhanced tool for invoice generation.
Rolandas Gricius, Igoris Belovas
doaj   +1 more source

Estimating the repeatability and reproducibility of an AI-embedded measuring device: Application to road markings [PDF]

EPJ Web of Conferences
The road markings inspection using on-board cameras is gaining popularity, particularly for road inspection, despite most research focusing on autonomous vehicles.
Bordet Térence, Redondin Maxime, Bornhofen Stefan, Denaës Sébastien, Histace Aymeric   +4 more
doaj   +1 more source