Results 191 to 200 of about 139,075 (261)

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Evaluating the Implementation of Online Postal Self-Sampling for Sexually Transmitted Infections in England: Multisite Qualitative Study.

J Med Internet Res
Spence T, Gibbs J, Wong G, Howarth A, Copas A, Crundwell D, Jackson L, Mercer CH, Mohammed H, Apea V, Day S, Ross J, Sullivan A, Winter A, Dewsnap C, Burns FM, Sheringham J.   +16 more
europepmc   +1 more source

Assessing the quality, reliability, and transparency of YouTube videos on spiritual palliative care: a content analysis. [PDF]

Front Public Health
Almobarak F.
europepmc   +1 more source

Feminist Commitment And Feminized Service: Nonprofits And Journals [PDF]

, 2010
White, Patricia
core   +2 more sources

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

Advanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu, Minhui Ouyang, Shufang Tan, Jianlin Guo, Ziqin Zhang, Xuan Liu, Risheng Liu, Hao Huang   +7 more
wiley   +1 more source

Policy context and digital development: a comparative study of trajectories in 4 Canadian academic health centers over 30 years. [PDF]

J Am Med Inform Assoc
Motulsky A, Usher S, Lehoux P, Régis C, Reay T, Hebert P, Gauvin L, Biron A, Baker GR, Moreault MP, Préval J, Denis JL.   +11 more
europepmc   +1 more source

Annual Report, 2009-2010 [PDF]

, 2010
Ammerman Center, Connecticut College
core   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

Analyses of historical documents reveal past trends of exploitation of manatees ( <i>Trichechus inunguis</i>) in the Amazon Basin (16th-19th centuries). [PDF]

Open Res Eur
Brito C, Garcia AC, Nicholls J, Silva J, Vieira N.   +4 more
europepmc   +1 more source

The possible impossible: from fractal philosophy to attunement [PDF]

, 2009
Golding, Sue, The University of Greenwich   +1 more
core