Results 31 to 40 of about 139,075 (261)
This article develops a dialectical questioning between the technological injunctions addressed to the cultural field of heritage so that it integrates digital devices, and the patrimonial experience actually proposed by these devices.
Marie Cambone
doaj +1 more source
DOCUMENTING THE CONSERVATIVE EVOLUTION OF THE CITY WALLS THANKS TO THE INTEGRATION OF DIGITAL SYSTEMS OF VARIOUS TYPOLOGIES. THE CASE STUDY OF VALBONA GATE [PDF]
The presented study describes how to document in a dynamic way a complex and full of historical information architecture with a flexible system. Thanks to the collaboration between various professional figures and the integration of various digital ...
L. Baratin +4 more
doaj +1 more source
Artefacts and Errors: Acknowledging Issues of Representation in the Digital: Imaging of Ancient Texts [PDF]
It is assumed, in palaeography, papyrology and epigraphy, that a certain amount of uncertainty is inherent in the reading of damaged and abraded texts.
Terras, Melissa M.
core +1 more source
Demanding stories: television coverage of sustainability, climate change and material demand [PDF]
This paper explores the past, present and future role of broadcasting, above all via the medium of television, in shaping how societies talk, think about and act on climate change and sustainability issues.
Allwood JA +17 more
core +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Objective. Formulate the general principles for the construction and operation of an integrated electronic document management system, as well as list the possibilities of document management automation.Method.
A. L. Zolkin, V. S. Tormozov
doaj +1 more source
Data fluidity in DARIAH -- pushing the agenda forward [PDF]
This paper provides both an update concerning the setting up of the European DARIAH infrastructure and a series of strong action lines related to the development of a data centred strategy for the humanities in the coming years.
Baillot, Anne +2 more
core +6 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source

