Results 141 to 150 of about 3,200,666 (325)

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

Advanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır, Yuan Fang, Consuelo Contreras, Andrew K. Schulz, Florian Hartmann   +4 more
wiley   +1 more source

An Approach of BIM-Based Dynamic Adaptive Zoning for Group Piles Construction Multi-Work Areas

Buildings
In large-scale pile foundation drilling projects, the absence of digital work area management hampers dynamic construction management, affecting efficiency.
Wei Zhou, Yunan Zhang, Jiaxi Chen, Haowen Jiang, Weijun You, Liangtao Nie, Mingjing Fang   +6 more
doaj   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Key Technologies for Intelligent Operation and Maintenance of Deep Drilling Top Drive Powered by Digital Twin

Shiyou jixie
To meet the key requirements of development of oil and gas resources in 10 000 m deep formation and intelligent operation and maintenance （O & M） of top drive in deep drilling， the key issues related to the prognostics and health management （PHM） of top ...
Wang Bo, Li Xianyi, Mi Kaifu, Liu Zeng, Tan Shuai, Li Xiang, Zhang Hang   +6 more
doaj   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

The Marysville, Montana Geothermal Project [PDF]

Drilling the first geothermal well in Montana presented many challenges, not only in securing materials and planning strategies for drilling the wildcat well but also in addressing the environmental, legal, and institutional issues raised by the request ...
Kuwada, J. T., Mcspadden, W. R., Stewart, D. H.   +2 more
core   +1 more source

Digital monitoring of rotary-percussive drilling with down-the-hole hammer for profiling weathered granitic ground

Journal of Rock Mechanics and Geotechnical Engineering, 2023
W. Yue, Siyuan Wu, Manchao He, Yafei Qiao, Z.Q. Yue   +4 more
semanticscholar   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Digital Selection Technology and Software Development of PDC Bit

Shiyou jixie
A large amount of engineering data related to formation and bit is generated in the course of drilling.Using big data analysis technology to optimize bit can be used to guide the selection,design and use of bit,thus shifting the selection of bit from ...
Ren Haitao, Wang Xindong, Zhang Xin, Yang Yingxin, Su Tao, Wang Baihui, Zhou Guangjing   +6 more
doaj