Results 91 to 100 of about 124,228 (379)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Integration of Digital Elevation Model (DEM) and HEC-RAS Hydrodynamic Model for flood routing

open access: yesIOP Conference Series: Materials Science and Engineering, 2019
Abstract The development of computer technology, especially the hydrodynamic modeling package, provides convenience in many things including flood modeling in the river. One of these modeling packages is HEC-RAS Hydrodynamic Model which can be used to simulate both steady flow and unsteady flow.
I. G. Tunas, Y. Arafat, H. Azikin
openaire   +2 more sources

A Versatile Processing Chain for Experimental TanDEM-X Product Evaluation [PDF]

open access: yes, 2010
TanDEM-X is a high-resolution interferometric mission with the main goal of providing a global digital elevation model (DEM) of the Earth surface by means of single-pass X-band SAR interferometry.
Krieger, Gerhard   +6 more
core  

Radar shadow detection in SAR images using DEM and projections

open access: yes, 2013
Synthetic aperture radar (SAR) images are widely used in target recognition tasks nowadays. In this letter, we propose an automatic approach for radar shadow detection and extraction from SAR images utilizing geometric projections along with the digital ...
Haddad, O., Prasath, V. B. S.
core   +2 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Investigating the use of UAV systems for photogrammetric applications : a case study of Ramla Bay (Gozo, Malta) [PDF]

open access: yes, 2017
In this study, we present the 3D digital model of Ramla Bay (Gozo) obtained by using photograms taken from drones. The high-resolution 3D model of Ramla Bay allowed the construction of a detailed Digital Elevation Model (DEM).
Cassar, Louis F.   +4 more
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Pemanfaatan Teknologi Lidar Dalam Analisis Genangan Banjir Akibat Luapan Sungai Berdasarkan Simulasi Model Hidrodinamik [PDF]

open access: yes, 2015
Flood analysis requires accurate topographic data to obtain a good overview of flood inundation. At this time, LIDAR (Light Detection and Ranging) is the best technology of remote sensing for collecting elevation data from earth surface.
Al Amin, M. Baitullah
core  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

ANALISA BATAS DAERAH ALIRAN SUNGAI DARI DATA ASTER GDEM TERHADAP DATA BPDAS (STUDI KASUS : SUB DAS BUNGBUNTU DAS TAROKAM)

open access: yesGeoid, 2015
Pemetaan batas daerah aliran sungai (DAS) merupakan salah satu parameter utama yang digunakan sebagai batasan penentuan kondisi tutupan lahan dan geomorfologi pada DAS.
Yogyrema Setyanto Putra, Muhammad Taufik
doaj   +1 more source

Home - About - Disclaimer - Privacy